PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 25346938-2 2014 Disturbances of tryptophan (TRP) metabolism might contribute to development of IFN-alpha-associated depression due to IFN-alpha-induced activation of indoleamine 2,3-dioxygenase (IDO), a rate-limiting enzyme of TRP-kynurenine (KYN) metabolism. 4,6-dichlorokynurenine 227-230 interferon alpha 1 Homo sapiens 79-88 25346938-2 2014 Disturbances of tryptophan (TRP) metabolism might contribute to development of IFN-alpha-associated depression due to IFN-alpha-induced activation of indoleamine 2,3-dioxygenase (IDO), a rate-limiting enzyme of TRP-kynurenine (KYN) metabolism. 4,6-dichlorokynurenine 227-230 interferon alpha 1 Homo sapiens 118-127