PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 34645465-0 2021 Activation of GPR39 with TC-G 1008 attenuates neuroinflammation via SIRT1/PGC-1alpha/Nrf2 pathway post-neonatal hypoxic-ischemic injury in rats. GPR39-C3 25-34 sirtuin 1 Rattus norvegicus 68-73 34645465-11 2021 Moreover, TC-G 1008 treatment significantly increased the expression of SIRT1, PGC-1alpha and Nrf2, but downregulated the expressions of IL-6, IL-1beta, and TNF-alpha. GPR39-C3 10-19 sirtuin 1 Rattus norvegicus 72-77 34645465-13 2021 CONCLUSIONS: TC-G 1008 attenuated neuroinflammation in part via the SIRT1/PGC-1alpha/Nrf2 pathway in a neonatal rat model of HIE. GPR39-C3 13-22 sirtuin 1 Rattus norvegicus 68-73