PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
29540733-3	2018	Glutamine is mainly metabolized through the glutaminolysis pathway and our previous report indicated that CtBP increases GDH activity and promotes glutaminolysis through repressing the expression of SIRT4, a well-known mitochondrion-located factor that inhibits glutaminolysis pathway.	ctbp	106-110	glutamate dehydrogenase 1	Homo sapiens	121-124	
29540733-9	2018	Consistently, the CtBP dimerization inhibitor MTOB mimicked low glucose effects on SIRT4 expression, and GDH activity suggest that CtBP requires high glucose supply to act as a suppressor of SIRT4 gene.	ctbp	131-135	glutamate dehydrogenase 1	Homo sapiens	105-108	
29540733-10	2018	In conclusion, we propose that a general molecular pathway composed by CtBP-SIRT4-GDH coordinating the metabolism of glucose and glutamine in cancer cells.	ctbp	71-75	glutamate dehydrogenase 1	Homo sapiens	82-85	
29540733-4	2018	CtBP is known to be a sensor of intracellular metabolic status; we thus hypothesized that a consensus CtBP-SIRT4-GDH axis may mediate the crosstalk between glycolysis and glutaminolysis.	ctbp	0-4	glutamate dehydrogenase 1	Homo sapiens	113-116	
29540733-4	2018	CtBP is known to be a sensor of intracellular metabolic status; we thus hypothesized that a consensus CtBP-SIRT4-GDH axis may mediate the crosstalk between glycolysis and glutaminolysis.	ctbp	102-106	glutamate dehydrogenase 1	Homo sapiens	113-116	
29540733-7	2018	Low level of glucose supply was found to decrease GDH activity via blocking CtBP dimerization.	ctbp	76-80	glutamate dehydrogenase 1	Homo sapiens	50-53