PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
23264848-8	2012	An analysis of the Tiam1 promoter revealed binding sites for the CtBP-interacting Kruppel-like factor 8 (KLF8), and a Tiam1 promoter luciferase reporter was induced in the presence of both KLF8 and CtBP2, consistent with KLF8-dependent CtBP transactivation of Tiam1.	ctbp	65-69	Kruppel like factor 8	Homo sapiens	189-193	
23264848-8	2012	An analysis of the Tiam1 promoter revealed binding sites for the CtBP-interacting Kruppel-like factor 8 (KLF8), and a Tiam1 promoter luciferase reporter was induced in the presence of both KLF8 and CtBP2, consistent with KLF8-dependent CtBP transactivation of Tiam1.	ctbp	65-69	Kruppel like factor 8	Homo sapiens	105-109	
23264848-8	2012	An analysis of the Tiam1 promoter revealed binding sites for the CtBP-interacting Kruppel-like factor 8 (KLF8), and a Tiam1 promoter luciferase reporter was induced in the presence of both KLF8 and CtBP2, consistent with KLF8-dependent CtBP transactivation of Tiam1.	ctbp	65-69	Kruppel like factor 8	Homo sapiens	189-193	
21416054-1	2011	KLF8 regulates target genes by recruiting the p300 and PCAF co-activators via glutamines (Q) 118 and 248, the CtBP co-repressor to 86PVDLS90 or SUMO to lysine (K) 67.	ctbp	110-114	Kruppel like factor 8	Homo sapiens	0-4	
21416054-6	2011	Interestingly, CtBP promoted sumoylation at K67 of wild-type but not AVALF mutant KLF8, and KLF8 interaction with CtBP was inhibited by treatment with the HDAC inhibitors, ectopic expression of the co-activators, or K93Q or K95Q mutation.	ctbp	114-118	Kruppel like factor 8	Homo sapiens	92-96	
21416054-7	2011	Promoter reporter assays showed that CtBP inhibited KLF8 transactivity which was rescued by PCAF or p300 expresson.	ctbp	37-41	Kruppel like factor 8	Homo sapiens	52-56	
21416054-9	2011	Taken together, these results identified a novel mechanism by which co-activators promote KLF8 transactivity by competing with SUMO for K67 modification and by acetylating K93 and K95 to inhibit CtBP-induced K67 sumoylation.	ctbp	195-199	Kruppel like factor 8	Homo sapiens	90-94