PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
17213307-4	2007	Treatment with the glycolytic blocker 2-deoxyglucose (2-DG) decreases association of the redox sensor CtBP with HIC1, an inhibitor of SIRT1 transcription.	ctbp	102-106	HIC ZBTB transcriptional repressor 1	Homo sapiens	112-116	
17213307-5	2007	We propose that the reduction in transcriptional repression mediated by HIC1, due to the decrease of CtBP binding, increases SIRT1 expression.	ctbp	101-105	HIC ZBTB transcriptional repressor 1	Homo sapiens	72-76	
12052894-0	2002	The human candidate tumor suppressor gene HIC1 recruits CtBP through a degenerate GLDLSKK motif.	ctbp	56-60	HIC ZBTB transcriptional repressor 1	Homo sapiens	42-46	
12052894-2	2002	Alignment of the HIC1 and HRG22 proteins from various species highlighted a perfectly conserved GLDLSKK/R motif highly related to the consensus CtBP interaction motif (PXDLSXK/R), except for the replacement of the virtually invariant proline by a glycine.	ctbp	144-148	HIC ZBTB transcriptional repressor 1	Homo sapiens	17-21	
12052894-3	2002	HIC1 strongly interacts with mCtBP1 both in vivo and in vitro through this conserved GLDLSKK motif, thus extending the CtBP consensus binding site.	ctbp	30-34	HIC ZBTB transcriptional repressor 1	Homo sapiens	0-4	
12052894-5	2002	When tethered to DNA by fusion with the Gal4 DNA-binding domain, the HIC1 central region represses transcription through interactions with CtBP in a trichostatin A-sensitive manner.	ctbp	139-143	HIC ZBTB transcriptional repressor 1	Homo sapiens	69-73	
12052894-6	2002	In conclusion, our results demonstrate that HIC1 mediates transcriptional repression by both HDAC-independent and HDAC-dependent mechanisms and show that CtBP is a HIC1 corepressor that is recruited via a variant binding site.	ctbp	154-158	HIC ZBTB transcriptional repressor 1	Homo sapiens	44-48	
12052894-6	2002	In conclusion, our results demonstrate that HIC1 mediates transcriptional repression by both HDAC-independent and HDAC-dependent mechanisms and show that CtBP is a HIC1 corepressor that is recruited via a variant binding site.	ctbp	154-158	HIC ZBTB transcriptional repressor 1	Homo sapiens	164-168	
22315224-4	2012	HIC1 encodes a transcriptional repressor with five C(2)H(2) zinc fingers mediating sequence-specific DNA binding and two repression domains: an N-terminal BTB/POZ domain and a central region recruiting CtBP and NuRD complexes.	ctbp	202-206	HIC ZBTB transcriptional repressor 1	Homo sapiens	0-4