PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 18164739-0 2008 Lathosterol side chain amides: a new class of human lathosterol oxidase inhibitors. Amides 23-29 sterol-C5-desaturase Homo sapiens 52-71 18164739-5 2008 In this paper we report on lathosterol side chain amides as a new class of selective lathosterol oxidase inhibitors. Amides 50-56 sterol-C5-desaturase Homo sapiens 85-104 18164739-7 2008 Small alkyl residues at the amide nitrogen (hydrogen and methyl) lead to an inhibition of the enzyme Delta24-reductase, the N-ethyl and N-propyl derivatives show a dual action, inhibiting both Delta24-reductase and lathosterol oxidase. Amides 28-33 sterol-C5-desaturase Homo sapiens 215-234 18164739-8 2008 Lathosterol-derived amides with larger substituents (butyl, isobutyl, tert-butyl, pentyl) at the amide nitrogen were found to be selective inhibitors of lathosterol oxidase. Amides 20-25 sterol-C5-desaturase Homo sapiens 153-172