PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
27253753-6	2017	Both the capacities to cleave DNA containing adenine:8OHG mispairs and to suppress mutations caused by 8OHG were significantly lower in prostatic cell lines with lower MUTYH expression than in prostatic cell lines with higher MUTYH expression.	8ohg	53-57	mutY DNA glycosylase	Homo sapiens	168-173	
27253753-6	2017	Both the capacities to cleave DNA containing adenine:8OHG mispairs and to suppress mutations caused by 8OHG were significantly lower in prostatic cell lines with lower MUTYH expression than in prostatic cell lines with higher MUTYH expression.	8ohg	103-107	mutY DNA glycosylase	Homo sapiens	168-173	
21826668-1	2011	The MUTYH gene encodes a DNA glycosylase that can initiate the excision repair of adenine mispaired with 8-hydroxyguanine (8OHG) and is responsible for a susceptibility to multiple colorectal adenomas and carcinomas.	8ohg	123-127	mutY DNA glycosylase	Homo sapiens	4-9	
23322991-1	2012	AIM: To investigate the suppressive activity of MUTYH variant proteins against mutations caused by oxidative lesion, 8-hydroxyguanine (8OHG), in human cells.	8ohg	135-139	mutY DNA glycosylase	Homo sapiens	48-53	
23322991-10	2012	The mutation frequency (4.7 x 10(-3)) of supF in the 8OHG-containing pMY189 plasmid in cells overexpressing WT MUTYH was significantly lower than in the empty vector cells (P < 0.01).	8ohg	53-57	mutY DNA glycosylase	Homo sapiens	111-116	
21826668-8	2011	MUTYH-over-expressing stable clones of the gastric cancer cell line AGS showed: (a) higher DNA cleavage activity towards adenine:8OHG mispair-containing substrates; (b) higher suppressive activity against mutations caused by 8OHG in a supF forward mutation assay; and (c) higher suppressive activity for cellular proliferation than empty vector-transfected AGS clones.	8ohg	129-133	mutY DNA glycosylase	Homo sapiens	0-5	
21826668-8	2011	MUTYH-over-expressing stable clones of the gastric cancer cell line AGS showed: (a) higher DNA cleavage activity towards adenine:8OHG mispair-containing substrates; (b) higher suppressive activity against mutations caused by 8OHG in a supF forward mutation assay; and (c) higher suppressive activity for cellular proliferation than empty vector-transfected AGS clones.	8ohg	225-229	mutY DNA glycosylase	Homo sapiens	0-5	
21826668-9	2011	These results suggested that MUTYH is a suppressor of mutations caused by 8OHG in gastric cells and that its reduced expression is associated with a poor prognosis in gastric cancer.	8ohg	74-78	mutY DNA glycosylase	Homo sapiens	29-34	
12807753-2	2003	In this study, we assessed the abilities of OGG1, MYH and APE1 proteins, which are components of a base excision repair pathway, to suppress G:C to T:A transversions caused by 8OHG or BPDE by a bacterial suppressor tRNA (supF) forward mutation assay using a shuttle plasmid, pMY189.	8ohg	176-180	mutY DNA glycosylase	Homo sapiens	50-53	
12807753-7	2003	These results indicate that OGG1 and MYH function as suppressors for G:C to T:A transversions by 8OHG but not by BPDE in human cells.	8ohg	97-101	mutY DNA glycosylase	Homo sapiens	37-40