PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 16851902-6 2005 In step 2, the adsorption of block copolymers on the surface of gold clusters takes place because of the amphiphilic character of the block copolymer (hydrophobicity of PPO). copolymers 35-45 protoporphyrinogen oxidase Homo sapiens 169-172 16851902-7 2005 The much higher efficiency of particle formation attained in the PEO-PPO-PEO block copolymer systems as compared to PEO homopolymer systems can be attributed to the adsorption and growth processes (steps 2 and 3) facilitated by the block copolymers. copolymers 238-248 protoporphyrinogen oxidase Homo sapiens 69-72 32228907-1 2020 This study investigates stabilization of graphene oxide (GO) nanosheets in polyethylene oxide-polypropylene oxide (PEO-PPO) block copolymers (P103, P123 and F127). copolymers 130-140 protoporphyrinogen oxidase Homo sapiens 119-122 15271568-4 2004 Block copolymers with comparably long PPO and PEO segment lengths, such as F127 and F108, most effectively protected DOPE liposomes prepared at high pH from aggregation and subsequent structural rearrangements induced by acidification. copolymers 6-16 protoporphyrinogen oxidase Homo sapiens 38-41 15271570-1 2004 The micellization of PEO-PPO-PEO block copolymers in p-xylene has been studied in the presence of CO2. copolymers 39-49 protoporphyrinogen oxidase Homo sapiens 25-28 15271570-5 2004 With the suitable composition and molecular weight, the critical micelle pressure (CMP) of copolymers decreases with the increase in the lengths of PEO and PPO blocks due to the hydrophilic and folding effects, respectively. copolymers 91-101 protoporphyrinogen oxidase Homo sapiens 156-159 15723471-0 2005 Lamellar-to-cubic phase change in phospholipid bilayer systems incorporated with block copolymers: DMPC and PEO-PPO-PEO (P85). copolymers 87-97 protoporphyrinogen oxidase Homo sapiens 112-115 15723476-1 2005 The drying of hydrogel films formed by poly(ethylene oxide)-poly(propylene oxide) (PEO-PPO) block copolymers (Pluronic P105 and Pluronic L64) is investigated at various air relative humidity (RH) conditions in the range 11-94%. copolymers 98-108 protoporphyrinogen oxidase Homo sapiens 87-90 15723476-8 2005 Two distinct regions (liquid/gel and solid/crystalline) are observed in the drying isotherm for PEO-PPO block copolymers and homopolymer poly(ethylene glycol)s. copolymers 110-120 protoporphyrinogen oxidase Homo sapiens 100-103 15212885-1 2004 The capability of a family of copolymers comprising Pluronic (PEO-PPO-PEO) surfactants covalently conjugated with poly(acrylic acid) (Pluronic-PAA) to enhance the aqueous solubility and stability of the lactone form of camptothecin (CPT) was studied. copolymers 30-40 protoporphyrinogen oxidase Homo sapiens 66-69 10814588-1 2000 Triblock copolymers of the form PEO(alpha)PPO(beta)PEO(alpha) [where PEO is poly(ethylene oxide) and PPO is poly(propylene oxide)] have many biomedical applications, many of which depend on the surface properties of the copolymers and the influence that those properties have on the adsorption of proteins. copolymers 9-19 protoporphyrinogen oxidase Homo sapiens 42-45 10814588-1 2000 Triblock copolymers of the form PEO(alpha)PPO(beta)PEO(alpha) [where PEO is poly(ethylene oxide) and PPO is poly(propylene oxide)] have many biomedical applications, many of which depend on the surface properties of the copolymers and the influence that those properties have on the adsorption of proteins. copolymers 9-19 protoporphyrinogen oxidase Homo sapiens 101-104 10814588-9 2000 As to the mechanism of protein resistance, our data support the proposal that sibling PEO segments of copolymers in condensed films fold back across their parental PPO cores, limiting access of proteins to the hydrophobic cores themselves. copolymers 102-112 protoporphyrinogen oxidase Homo sapiens 164-167 10767140-1 2000 The solubilization of five hydrophilic water-soluble aroma compounds in self-aggregating triblock amphiphilic copolymers of poly(ethylene oxide)-poly(propylene oxide)-poly(ethylene oxide) (PEO-PPO-PEO), with similar percentages of PEO and different molecular weights, was studied. copolymers 110-120 protoporphyrinogen oxidase Homo sapiens 193-196 9885264-4 1999 It shows that the relative intensities of several peaks in Raman spectra are dependent on the PPO/PEO ratios and the conformation of the copolymers. copolymers 137-147 protoporphyrinogen oxidase Homo sapiens 94-97 9885264-6 1999 Other block copolymers exhibit that the disordered structure increases with increasing PPO/PEO ratio. copolymers 12-22 protoporphyrinogen oxidase Homo sapiens 87-90 34826745-1 2022 Pluronic (PEO-PPO-PEO) block copolymers can form nano-sized micelles with a structure composed of a hydrophobic PPO core and hydrophilic PEO shell layer. copolymers 29-39 protoporphyrinogen oxidase Homo sapiens 14-17 34826745-1 2022 Pluronic (PEO-PPO-PEO) block copolymers can form nano-sized micelles with a structure composed of a hydrophobic PPO core and hydrophilic PEO shell layer. copolymers 29-39 protoporphyrinogen oxidase Homo sapiens 112-115 30966142-6 2018 However, parent copolymers with distinct PPO moieties do not affirmatively lead to non-cooperative binding, such as the L92 + P84 system. copolymers 16-26 protoporphyrinogen oxidase Homo sapiens 41-44 31117745-0 2019 Influence of Cholesterol and Bilayer Curvature on the Interaction of PPO-PEO Block Copolymers with Liposomes. copolymers 83-93 protoporphyrinogen oxidase Homo sapiens 69-72 31117745-1 2019 Interactions of nonionic poly(ethylene oxide)- b-poly(propylene oxide) (PEO-PPO) block copolymers, known as Pluronics or poloxamers, with cell membranes have been widely studied for a host of biomedical applications. copolymers 87-97 protoporphyrinogen oxidase Homo sapiens 76-79 25630439-2 2016 AIM: This article aims to investigate the effect of poly(ethylene oxide)-poly(propylene oxide) (PEO-PPO) block copolymers with a wide range of biomedical and pharmaceutical applications on apoptosis and/or cell immortalization, by flow cytometry and multiplex RT-PCR for bax, bcl-2, and human telomerase reverse transcriptase (hTERT). copolymers 111-121 protoporphyrinogen oxidase Homo sapiens 100-103 25630439-4 2016 CONCLUSIONS: PEO-PPO block copolymers-considered safe for human use-can drastically alter gene expression profiles of genes related to apoptosis/cell proliferation. copolymers 27-37 protoporphyrinogen oxidase Homo sapiens 17-20 25736430-1 2015 Case study of PEO and its PPO-PEO diblock copolymers. copolymers 42-52 protoporphyrinogen oxidase Homo sapiens 26-29 26625137-8 2015 A PTFE dispersion containing P123 showed the maximum wettability and lowest sedimentation among the series of block copolymers introduced, which is attributed to faster diffusion kinetics and a higher PPO contribution fostering faster adsorption at the PTFE surface. copolymers 116-126 protoporphyrinogen oxidase Homo sapiens 201-204 26115534-1 2015 Interactions of X-shaped poly(ethylene oxide)-poly(propylene oxide) (PEO-PPO) block copolymers with cell membranes were investigated recording the pi-A isotherms of monolayer systems of dipalmitoylphosphatidylcholine (DPPC):cholesterol 100:0; 80:20 and 60:40 mol ratio and evaluating the capability of the copolymers to trigger haemolysis or to protect from haemolytic agents. copolymers 84-94 protoporphyrinogen oxidase Homo sapiens 73-76 25736430-2 2015 Stability and reorganization in Langmuir films of PEO in PEO homopolymers and PPO-PEO block copolymers were investigated using film balance measurements. copolymers 92-102 protoporphyrinogen oxidase Homo sapiens 78-81 25807174-4 2015 Within the Langmuir-trough, PEO-b-PPO acts as the most effective amphiphile compared to the other PPO-containing copolymers. copolymers 113-123 protoporphyrinogen oxidase Homo sapiens 98-101 21855892-0 2011 Effect of pH on the single-step synthesis of gold nanoparticles using PEO-PPO-PEO triblock copolymers in aqueous media. copolymers 91-101 protoporphyrinogen oxidase Homo sapiens 74-77 23211870-0 2013 Synthesis, characterization, and self-assembly of linear poly(ethylene oxide)-block-poly(propylene oxide)-block-poly(epsilon-caprolactone) (PEO-PPO-PCL) copolymers. copolymers 153-163 protoporphyrinogen oxidase Homo sapiens 144-147 22575779-1 2012 The conformation and the dilatational properties of three non-ionic triblock PEO-PPO-PEO (where PEO is polyethyleneoxide and PPO is polypropyleneoxide) copolymers of different hydrophobicity and molecular weight were investigated at the water-hexane interface. copolymers 152-162 protoporphyrinogen oxidase Homo sapiens 81-84 23256509-1 2013 The phase behavior of two types of poly(ethylene oxide)/poly(propylene oxide) (PEO/PPO) copolymers in aqueous solutions was studied by light scattering, viscometry, and infrared spectroscopy. copolymers 88-98 protoporphyrinogen oxidase Homo sapiens 83-86 23099248-1 2013 Amphiphilic block copolymers of the poly(ethylene oxide)-poly(propylene oxide) (PEO-PPO) family (commercially available as Pluronics or Poloxamers) are well-known for self-assembling in water (selective solvent for PEO) into micelles with a PPO-rich core and a hydrated PEO corona. copolymers 18-28 protoporphyrinogen oxidase Homo sapiens 84-87 23099248-1 2013 Amphiphilic block copolymers of the poly(ethylene oxide)-poly(propylene oxide) (PEO-PPO) family (commercially available as Pluronics or Poloxamers) are well-known for self-assembling in water (selective solvent for PEO) into micelles with a PPO-rich core and a hydrated PEO corona. copolymers 18-28 protoporphyrinogen oxidase Homo sapiens 241-244 22392332-0 2012 Relationship between the affinity of PEO-PPO-PEO block copolymers for biological membranes and their cellular effects. copolymers 55-65 protoporphyrinogen oxidase Homo sapiens 41-44 22392332-1 2012 PURPOSE: The interactions of poly(ethylene oxide)-co-poly(propylene oxide) tri-block copolymers (PEO-PPO-PEO block copolymers, Pluronics , Synperonics , Poloxamers) of differing chemical composition with cell membranes were systematically investigated in order to clarify the mechanisms behind their previously reported various cellular responses. copolymers 85-95 protoporphyrinogen oxidase Homo sapiens 101-104 21563804-1 2011 A series of poly(propylene oxide)-b-poly(L-lysine) (PPO-PK) block copolymers were synthesized using Huisgen"s 1,3-dipolar cycloaddition, and the solution self-assembly was studied using transmission electron microscopy, circular dichroism spectroscopy, and dynamic and static light scattering techniques. copolymers 66-76 protoporphyrinogen oxidase Homo sapiens 52-55 20167328-2 2010 For identical PEO/PPO ratios, copolymers with lower molecular weight show a larger increase in the cloud point in the presence of surfactants than polymers with higher molecular weight. copolymers 30-40 protoporphyrinogen oxidase Homo sapiens 18-21 21123038-0 2011 Micelles from PEO-PPO-PEO block copolymers as nanocontainers for solubilization of a poorly water soluble drug hydrochlorothiazide. copolymers 32-42 protoporphyrinogen oxidase Homo sapiens 18-21 18838162-6 2009 During the self-assembly, the PPO blocks of both block copolymers aggregated into cores that were surrounded by mixed corona chains of PLGA and PEG blocks. copolymers 55-65 protoporphyrinogen oxidase Homo sapiens 30-33 20151706-7 2010 In (EO)(m)(PO)(n)(EO)(m) block copolymers, this process is complicated by the stripping of PEO chains of a part of hydrogen-bound water and entwining them with PPO. copolymers 31-41 protoporphyrinogen oxidase Homo sapiens 160-163 17655339-0 2007 1H NMR spectroscopic investigations on the micellization and gelation of PEO-PPO-PEO block copolymers in aqueous solutions. copolymers 91-101 protoporphyrinogen oxidase Homo sapiens 77-80 18769873-3 2008 METHODS: We synthesized new amphiphilic copolymers in which the hydrophobic pPO block was replaced by poly(tetrahydrofuran) (pTHF) chains. copolymers 40-50 protoporphyrinogen oxidase Homo sapiens 76-79 18710282-0 2008 Thiol/acrylate-modified PEO-PPO-PEO triblocks used as reactive and thermosensitive copolymers. copolymers 83-93 protoporphyrinogen oxidase Homo sapiens 28-31 19198429-2 2008 The copolymers were grafted with enantiomeric oligo(L-lactic acid) or oligo(D-lactic acid) chains using ring opening polymerization onto the PPO segment. copolymers 4-14 protoporphyrinogen oxidase Homo sapiens 141-144 18081338-3 2008 Random copolymers displayed an interaction similar to that observed with other hydrophilic homopolymers with the additional characteristic that the intensity of the interaction increased with the increase in the copolymer hydrophobicity (as determined by its PO content), revealing that these copolymers display an intermediate behavior between PEO and PPO. copolymers 7-17 protoporphyrinogen oxidase Homo sapiens 353-356 18081338-3 2008 Random copolymers displayed an interaction similar to that observed with other hydrophilic homopolymers with the additional characteristic that the intensity of the interaction increased with the increase in the copolymer hydrophobicity (as determined by its PO content), revealing that these copolymers display an intermediate behavior between PEO and PPO. copolymers 293-303 protoporphyrinogen oxidase Homo sapiens 353-356 17279703-2 2007 PEO/PPO block-copolymers are generally soluble in xylene but without forming aggregates. copolymers 14-24 protoporphyrinogen oxidase Homo sapiens 4-7 17253738-0 2007 Effect of ionic liquids on the aggregation behavior of PEO-PPO-PEO block copolymers in aqueous solution. copolymers 73-83 protoporphyrinogen oxidase Homo sapiens 59-62 17481869-5 2007 The present review provides a concise description of the most important applications of PEO-PPO-based copolymers in the Pharmaceutical Technology field as means for attaining improved solubility, stability, release, and bioavailability of drugs. copolymers 102-112 protoporphyrinogen oxidase Homo sapiens 92-95 17439172-3 2007 Such interactions influence the self-assembly properties of the block copolymer in solution by increasing the hydration of the block copolymers and stabilizing the gauche conformation of the PPO chain. copolymers 133-143 protoporphyrinogen oxidase Homo sapiens 191-194 17439172-4 2007 Therefore, urea increases the critical micellization temperature (CMT) values of PEO-PPO-PEO copolymers, and the effect of urea on the CMT is more pronounced for copolymers with higher PEO contents and lower for those with increased contents of PPO segments. copolymers 93-103 protoporphyrinogen oxidase Homo sapiens 85-88 16563878-0 2006 Preparation of biosensors by immobilization of polyphenol oxidase in conducting copolymers and their use in determination of phenolic compounds in red wine. copolymers 80-90 protoporphyrinogen oxidase Homo sapiens 47-65 16563878-4 2006 Novel biosensors for phenolic compounds were constructed by immobilizing polyphenol oxidase (PPO) into conducting copolymers prepared by electropolymerization of pyrrole with thiophene capped polytetrahydrofuran. copolymers 114-124 protoporphyrinogen oxidase Homo sapiens 73-91 16563878-4 2006 Novel biosensors for phenolic compounds were constructed by immobilizing polyphenol oxidase (PPO) into conducting copolymers prepared by electropolymerization of pyrrole with thiophene capped polytetrahydrofuran. copolymers 114-124 protoporphyrinogen oxidase Homo sapiens 93-96