PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
27154500-0	2016	Synthesis of intracellular reduction-sensitive amphiphilic polyethyleneimine and poly(epsilon-caprolactone) graft copolymer for on-demand release of doxorubicin and p53 plasmid DNA.	copolymer	114-123	tumor protein p53	Homo sapiens	165-168	
27154500-10	2016	Finally, the co-delivery of Dox and p53-pDNA using the copolymer displayed greater cytotoxic effect compared with the Dox-loaded nanoparticle counterpart as revealed by cell viability and Caspase 3 expression assay.	copolymer	55-64	tumor protein p53	Homo sapiens	36-39	
27154500-16	2016	In addition, the co-delivery of doxorubicin and p53 plasmid DNA using the new copolymer displayed greater cytotoxic effect compared with single agent (i.e. Dox) loaded counterpart, which indicated the significance of rapid dissociation of therapeutic agents from the carrier for synergistic cytotoxic effects on cancer cells.	copolymer	78-87	tumor protein p53	Homo sapiens	48-51	
30863051-1	2019	Background: An amphiphilic cationic copolymer cholesterol-g-poly(amine-co-ester), namely Chol-g-PMSC-PPDL synthesized in a chemoenzymatic route has been utilized as a carrier for p53 gene delivery to check its antitumor efficacy, using human prostate cancer cell line PC-3 (p53 null) as a model.	copolymer	36-45	tumor protein p53	Homo sapiens	179-182	
30863051-1	2019	Background: An amphiphilic cationic copolymer cholesterol-g-poly(amine-co-ester), namely Chol-g-PMSC-PPDL synthesized in a chemoenzymatic route has been utilized as a carrier for p53 gene delivery to check its antitumor efficacy, using human prostate cancer cell line PC-3 (p53 null) as a model.	copolymer	36-45	tumor protein p53	Homo sapiens	274-277	
33001126-6	2020	The PCL-ss-P(PEGMA-co-GHA) amphiphilic copolymer could self-assemble into nanoparticles, which could be used to encapsulate anticancer drug doxorubicin (DOX) and compress the p53 gene to form the DOX-loaded PCL-ss-P(PEGMA-co-GHA)/p53 complex (abbreviated as DPGHAP/p53).	copolymer	39-48	tumor protein p53	Homo sapiens	175-178	
33001126-6	2020	The PCL-ss-P(PEGMA-co-GHA) amphiphilic copolymer could self-assemble into nanoparticles, which could be used to encapsulate anticancer drug doxorubicin (DOX) and compress the p53 gene to form the DOX-loaded PCL-ss-P(PEGMA-co-GHA)/p53 complex (abbreviated as DPGHAP/p53).	copolymer	39-48	tumor protein p53	Homo sapiens	230-233	
33001126-6	2020	The PCL-ss-P(PEGMA-co-GHA) amphiphilic copolymer could self-assemble into nanoparticles, which could be used to encapsulate anticancer drug doxorubicin (DOX) and compress the p53 gene to form the DOX-loaded PCL-ss-P(PEGMA-co-GHA)/p53 complex (abbreviated as DPGHAP/p53).	copolymer	39-48	tumor protein p53	Homo sapiens	258-269	
31923958-2	2020	To this end, we constructed a novel UV-light cross-linked and pH de-cross-linked coumarin-decorated cationic copolymer functionalized mesoporous silica nanoparticles (MSN) for co-delivery of chemotherapeutic agent 5-FU and tumor suppresser p53 gene.	copolymer	109-118	tumor protein p53	Homo sapiens	240-243