PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
18620444-2	2008	Here, a pH-responsive copolymer, poly(2-(dimethylamino)ethyl methacrylate)- b-poly(2-(diethylamino)ethyl methacrylate) (PDMA(106)- b-PDEA(25)), has been used to study the formation and dissociation of adsorbed micelles through pH variation.	copolymer	22-31	phosphodiesterase 6A	Homo sapiens	133-137	
18755475-3	2008	For the copolymer, the limiting area per segment versus temperature shows a break point around 29 degrees C, slightly lower than the lower critical solution temperature (LCST) of h-PDEA in water (31-33 degrees C).	copolymer	8-17	phosphodiesterase 6A	Homo sapiens	181-185	
17935731-2	2008	In acidic solution, this copolymer forms core-shell micelles with the neutral PMAA chains being located in the hydrophobic cores and the protonated PDEA chains forming the cationic micelle coronas.	copolymer	25-34	phosphodiesterase 6A	Homo sapiens	148-152	
17935731-3	2008	In alkaline solution, the copolymer forms the analogous inverted micelles with anionic PMAA coronas and hydrophobic PDEA cores.	copolymer	26-35	phosphodiesterase 6A	Homo sapiens	116-120	
28119221-6	2017	As the mole concentration of copolymer is increased from 10% to 50%, the microstructures formed by PCL-PDEA-PSBMA and DOX remains spherical micelles whereas PCL-PDEA-PEGMA undergoes structural transition from spherical to cylindrical and finally to lamellar micelles.	copolymer	29-38	phosphodiesterase 6A	Homo sapiens	103-107	
28778054-4	2017	A triblock amphiphilic copolymer, methoxy-poly(ethylene glycol) 2000-poly(2-(N,N-diethylamino)ethyl methacrylate)-polycaprolactone (mPEG-PDEA-PCL, PDC), was used to load paclitaxel (PTX), a hydrophobic anticancer agent, using an injection method.	copolymer	23-32	phosphodiesterase 6A	Homo sapiens	137-141	
17241021-2	2007	Well-defined double hydrophilic miktoarm AB4 star copolymer, PNIPAM-b-(PDEA)4, was then synthesized by polymerizing 2-(diethylamino)ethyl methacrylate (DEA) via ATRP in 2-propanol at 45 degrees C using 1b, where PDEA was poly(2-(diethylamino)ethyl methacrylate).	copolymer	50-59	phosphodiesterase 6A	Homo sapiens	71-75	
17241021-2	2007	Well-defined double hydrophilic miktoarm AB4 star copolymer, PNIPAM-b-(PDEA)4, was then synthesized by polymerizing 2-(diethylamino)ethyl methacrylate (DEA) via ATRP in 2-propanol at 45 degrees C using 1b, where PDEA was poly(2-(diethylamino)ethyl methacrylate).	copolymer	50-59	phosphodiesterase 6A	Homo sapiens	212-216	
16930613-1	2006	The pH-responsive behavior of adsorbed diblock copolymer films of PDMA-PDEA (poly(2-(dimethylamino)ethyl methacrylate)-block-poly(2-(diethylamino)ethyl methacrylate)) on silica has been characterized using a quartz crystal microbalance with dissipation monitoring (QCM-D), an optical reflectometer (OR) and an atomic force microscope (AFM).	copolymer	47-56	phosphodiesterase 6A	Homo sapiens	66-75	
16869582-4	2006	As a result, the adsorption behavior of PDMA-PDEA diblock copolymers on silica is strongly dependent on both the copolymer concentration and the solution pH.	copolymer	58-67	phosphodiesterase 6A	Homo sapiens	45-49	
28119221-6	2017	As the mole concentration of copolymer is increased from 10% to 50%, the microstructures formed by PCL-PDEA-PSBMA and DOX remains spherical micelles whereas PCL-PDEA-PEGMA undergoes structural transition from spherical to cylindrical and finally to lamellar micelles.	copolymer	29-38	phosphodiesterase 6A	Homo sapiens	161-165	
33429519-3	2015	A four-armed star copolymer, tetra-(methoxy-poly(ethylene glycol)-poly(2-(N,N-diethylamino)ethyl methacrylate)-poly(epsilon-caprolactone) pentaerythritol ((mPEG-pDEA-PCL)4-PET, PDCP), was synthesized via the ring-opening polymerization, atom transfer radical polymerization and click chemistry, which formed a monomolecular nanocarrier in water.	copolymer	18-27	phosphodiesterase 6A	Homo sapiens	161-165	
24874300-5	2014	Specifically, the synergistic effect of temperature and pH was observed, and the hydrogen bonding between PDEA and PMAA components in the copolymer played a key role for this.	copolymer	138-147	phosphodiesterase 6A	Homo sapiens	106-110