PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 23022345-4 2012 Here we examine the capacity of fibrous poly epsilon-caprolactone (PCL) scaffolds, biofunctionalised with immobilised glial cell-derived neurotrophic factor (GDNF), to influence primary cortical neural stem cells/progenitors in vitro and enhance integration of these cells following transplantation into the brain parenchyma. polycaprolactone 67-70 glial cell derived neurotrophic factor Homo sapiens 118-156 23022345-6 2012 In vitro, we demonstrate that PCL with immobilised GDNF (iGDNF) significantly enhances cell viability and neural stem cell/progenitor proliferation compared to conventional 2-dimensional cultureware. polycaprolactone 30-33 glial cell derived neurotrophic factor Homo sapiens 51-55 25786730-0 2014 Controlled release of glial cell line-derived neurotrophic factor from poly(epsilon-caprolactone) microspheres. polycaprolactone 71-97 glial cell derived neurotrophic factor Homo sapiens 22-65 25786730-3 2014 As a proof of concept, we encapsulated GDNF into poly(epsilon-caprolactone) (PCL) microspheres to enable controlled drug release for 25 days. polycaprolactone 49-75 glial cell derived neurotrophic factor Homo sapiens 39-43 25786730-3 2014 As a proof of concept, we encapsulated GDNF into poly(epsilon-caprolactone) (PCL) microspheres to enable controlled drug release for 25 days. polycaprolactone 77-80 glial cell derived neurotrophic factor Homo sapiens 39-43 32262904-4 2015 This work focuses on designing a novel class of encapsulated poly(epsilon-caprolactone) (PCL) nanofiber scaffolds with different topographies (random and aligned) that generate controlled release of GDNF to potentially serve as a suitable substitute for the dura mater during neurosurgical procedures. polycaprolactone 61-87 glial cell derived neurotrophic factor Homo sapiens 199-203 32262904-4 2015 This work focuses on designing a novel class of encapsulated poly(epsilon-caprolactone) (PCL) nanofiber scaffolds with different topographies (random and aligned) that generate controlled release of GDNF to potentially serve as a suitable substitute for the dura mater during neurosurgical procedures. polycaprolactone 89-92 glial cell derived neurotrophic factor Homo sapiens 199-203 24700461-6 2014 Enzyme-linked immunosorbent assays (ELISA) revealed that GDNF, covalently tethered onto polycaprolactone (PCL) electrospun nanofibrous scaffolds, remained present on the scaffold surface for 120 days, with no evidence of protein leaching or degradation. polycaprolactone 88-104 glial cell derived neurotrophic factor Homo sapiens 57-61 24700461-6 2014 Enzyme-linked immunosorbent assays (ELISA) revealed that GDNF, covalently tethered onto polycaprolactone (PCL) electrospun nanofibrous scaffolds, remained present on the scaffold surface for 120 days, with no evidence of protein leaching or degradation. polycaprolactone 106-109 glial cell derived neurotrophic factor Homo sapiens 57-61