PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 20933540-2 2011 Firstly, amino-remained chitosan-graft-poly (e-caprolactone) (CS-g-PCL) was synthesized with a facile one-step manner by grafting e-caprolactone oligomers onto the hydroxyl groups of CS via ring-opening polymerization by using methanesulfonic acid as solvent and catalyst. polycaprolactone 45-59 polycystic kidney disease 2-like 1 Mus musculus 67-70 20047821-2 2010 In particular, cationic chitosan-graft-polycaprolactone (CS-g-PCL) copolymers were synthesized with a facile one-pot manner via ring-opening polymerization of epsilon-CL onto the hydroxyl groups of CS by using methanesulfonic acid as solvent and catalyst. polycaprolactone 39-55 polycystic kidney disease 2-like 1 Mus musculus 62-65 21499434-2 2011 In the present study, cationic chitosan-graft-poly(e-caprolactone)/polycaprolactone (CS-PCL/PCL) hybrid scaffolds were successfully prepared by electrospinning. polycaprolactone 67-83 polycystic kidney disease 2-like 1 Mus musculus 85-95 29287231-2 2018 Poly(epsilon-caprolactone)/PCL is widely used in medical devices, tissue engineering, and drug delivery systems. polycaprolactone 0-26 polycystic kidney disease 2-like 1 Mus musculus 27-30 19736995-1 2009 Biodegradable poly(epsilon-caprolactone)/poly(ethylene glycol) (PCL/PEG) copolymer nanoparticles showed potential application in drug delivery systems. polycaprolactone 14-40 polycystic kidney disease 2-like 1 Mus musculus 64-67 19736995-2 2009 In this article, monodisperse poly(epsilon-caprolactone)/poly(ethylene glycol)/poly(epsilon-caprolactone) (PCL/PEG/PCL, PCEC) nanoparticles, approximately 40 nm, were prepared by solvent extraction method using acetone as the organic solvent. polycaprolactone 30-56 polycystic kidney disease 2-like 1 Mus musculus 107-110 19736995-2 2009 In this article, monodisperse poly(epsilon-caprolactone)/poly(ethylene glycol)/poly(epsilon-caprolactone) (PCL/PEG/PCL, PCEC) nanoparticles, approximately 40 nm, were prepared by solvent extraction method using acetone as the organic solvent. polycaprolactone 79-105 polycystic kidney disease 2-like 1 Mus musculus 107-110 34993184-2 2021 We have previously reported the successful regeneration of good-quality cartilage in a nude mouse model using the electrospun gelatin/polycaprolactone (GT/PCL) nanofiber membranes. polycaprolactone 134-150 polycystic kidney disease 2-like 1 Mus musculus 155-158 34474864-3 2021 Here, we engineered a BMAT analog made of a GelMA (gelatin methacryloyl) hydrogel/medical-grade polycaprolactone (mPCL) scaffold composite to structurally and biologically mimic key aspects of the bone marrow microenvironment, and exploited an innovative bioreactor to study the effects of mechanical loading. polycaprolactone 96-112 polycystic kidney disease 2-like 1 Mus musculus 114-118 33869154-2 2021 Biodegradable medical-grade polycaprolactone (mPCL) scaffolds designed and rooted in evidence-based research offer a promising alternative to overcome the limitations of routinely used silicone implants for breast reconstruction. polycaprolactone 28-44 polycystic kidney disease 2-like 1 Mus musculus 46-50 35335450-3 2022 Herein, poly (epsilon-caprolactone) (PCL) and poly (lactic-co-glycolic acid) (PLGA) polymers were used to make scaffolds and were functionalized with peptides (RGD (Arginine-glycine-aspartate), VEGF (Vascular endothelial growth factor), laminin) or gelatin to augment engraftment. polycaprolactone 8-35 polycystic kidney disease 2-like 1 Mus musculus 37-40 33307369-1 2021 Biomimetically designed medical-grade polycaprolactone (mPCL) dressings are 3D-printed with pore architecture and anisotropic mechanical characteristics that favor skin wound healing with reduced scarring. polycaprolactone 38-54 polycystic kidney disease 2-like 1 Mus musculus 56-60 30325093-3 2018 In this work, the potential of three-dimensional (3D) nanofibrous graphene and poly(caprolactone) (PCL + G) composite scaffold for cardiac tissue engineering has been explored for the first time. polycaprolactone 79-97 polycystic kidney disease 2-like 1 Mus musculus 99-102 33039595-2 2020 Thus, we locally applied 3D-printed medical-grade polycaprolactone (mPCL) scaffolds loaded with Doxorubicin (DOX) and measured its effect in a humanized primary bone cancer model. polycaprolactone 50-66 polycystic kidney disease 2-like 1 Mus musculus 68-72 30940304-5 2019 In this study, leflunomide-loaded poly(epsilon-caprolactone) implants (leflunomide PCL implants) were evaluated as local drug delivery systems capable of attenuating inflammation and angiogenesis, which represent events of synovitis. polycaprolactone 34-60 polycystic kidney disease 2-like 1 Mus musculus 83-86 28374682-3 2017 Melt electrospinning writing allows the design and fabrication of medical grade polycaprolactone (mPCL) fibrous networks for the reinforcement of soft hydrogel matrices for cartilage tissue engineering. polycaprolactone 80-96 polycystic kidney disease 2-like 1 Mus musculus 98-102 29909312-4 2018 The traditional Chinese medicine icariin (ICA) was subsequently introduced into poly (epsilon-caprolactone) (PCL) /gelatin nanofibers to fabricate an artificial periosteum for the first time. polycaprolactone 80-107 polycystic kidney disease 2-like 1 Mus musculus 109-112 29642582-2 2018 The aim of this study was to develop a new anti-inflammatory scaffold by functionalizing an electrospun nanofibrous poly-epsilon-caprolactone membrane with IBU (IBU-PCL) and to evaluate its impact on periodontal inflammation, wound healing and regeneration in vitro and in vivo. polycaprolactone 116-141 polycystic kidney disease 2-like 1 Mus musculus 165-168 28240815-3 2017 In this study, the authors describe the development and characterization of a GBR membrane made of medical grade polycaprolactone (mPCL) electrospun fibers with antibacterial and immunomodulatory properties. polycaprolactone 113-129 polycystic kidney disease 2-like 1 Mus musculus 131-135 28032906-2 2017 This study assessed the mineralized tissue forming potential of 3-D printed medical grade polycaprolactone (mPCL) constructs containing osteoblasts (OB) encapsulated in a hyaluronic acid (HA)-hydrogel incorporating bone morphogenetic protein-7 (BMP-7). polycaprolactone 90-106 polycystic kidney disease 2-like 1 Mus musculus 108-112 26906227-1 2016 In the study presented here, in order to improve the surface functionality and topography of poly (epsilon-caprolactone) (PCL)/chitosan/PCL hybrid tissue scaffolds fabricated layer by layer with electrospinning technique, an atmospheric pressure nozzle type plasma surface modification was utilized. polycaprolactone 93-120 polycystic kidney disease 2-like 1 Mus musculus 122-125 26883261-0 2017 Structural and Surface Compatibility Study of Modified Electrospun Poly(epsilon-caprolactone) (PCL) Composites for Skin Tissue Engineering. polycaprolactone 67-93 polycystic kidney disease 2-like 1 Mus musculus 95-98 22965926-1 2013 In this article, the plasma surface modification effects on the chemical, mechanical, and biological properties of electrospun poly (epsilon-caprolactone) (PCL) random nanofiber meshes (NFMs) were investigated by adjusting plasma chemistry, that is, using glow discharges of N(2) +H(2), NH(3) +O(2), and Ar+O(2) gas mixtures. polycaprolactone 127-154 polycystic kidney disease 2-like 1 Mus musculus 156-159 23493403-2 2013 In this work, biodegradable micelles made from star-shaped poly(epsilon-caprolactone)/poly(ethylene glycol) (PCL/PEG) copolymer were prepared and used to deliver doxorubicin (Dox) in vitro and in vivo. polycaprolactone 59-85 polycystic kidney disease 2-like 1 Mus musculus 109-112