PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 12392815-8 2002 A consequence of reduced beta-catenin in SW480 cells was that exisulind, CP461, and CP248 caused a concentration- and time-dependent decrease in cyclin D1 levels (EC(50) approximately 300 microM, 1 microM, and <1 microM, respectively) in 4 hr. sulindac sulfone 84-89 cyclin D1 Homo sapiens 145-154 16382042-4 2005 Sulindac sulfone was consistently more potent than the sulfide metabolite in all analyses, significantly decreasing the expression of total cellular beta-catenin (50% of control), pro-caspase 3 (49%), cyclin D1 (51%), and PPARdelta (65%) in SW480 cells. sulindac sulfone 0-16 cyclin D1 Homo sapiens 201-210