PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
14570700-6	2004	PGC-1alpha content in EPI was increased after 18-h in vitro incubation with 0.5 mM 5-aminoimidazole-4-carboxamide ribonucleoside (AICAR) and 4 mM caffeine.	acadesine	83-128	PPARG coactivator 1 alpha	Rattus norvegicus	0-10	
14570700-6	2004	PGC-1alpha content in EPI was increased after 18-h in vitro incubation with 0.5 mM 5-aminoimidazole-4-carboxamide ribonucleoside (AICAR) and 4 mM caffeine.	acadesine	130-135	PPARG coactivator 1 alpha	Rattus norvegicus	0-10	
22496244-8	2012	Surprisingly, AICAR-induced increases in PGC-1alpha mRNA levels were greater in skeletal muscle from HFD-fed rats.	acadesine	14-19	PPARG coactivator 1 alpha	Rattus norvegicus	41-51	
26239887-9	2015	Similarly, the AMPK agonists 5-aminoimidazole-4-carboxamide riboside and resveratrol significantly increased the mRNA expression levels of PGC-1alpha and NRF-2alpha in cultured neurons.	acadesine	29-68	PPARG coactivator 1 alpha	Rattus norvegicus	139-149	
25388945-4	2015	Rats were treated with AICAR (1 mg/g body weight/day) for 14 days, resulting in increased expression levels of nicotinamide phosphoribosyltransferase (NAMPT), peroxisome proliferator-activated receptor-gamma coactivator-1alpha (PGC-1alpha), glucose transporter 4 proteins, and enhanced mitochondrial biogenesis.	acadesine	23-28	PPARG coactivator 1 alpha	Rattus norvegicus	159-226	
25388945-4	2015	Rats were treated with AICAR (1 mg/g body weight/day) for 14 days, resulting in increased expression levels of nicotinamide phosphoribosyltransferase (NAMPT), peroxisome proliferator-activated receptor-gamma coactivator-1alpha (PGC-1alpha), glucose transporter 4 proteins, and enhanced mitochondrial biogenesis.	acadesine	23-28	PPARG coactivator 1 alpha	Rattus norvegicus	228-238	
20438809-7	2010	Similarly, pharmacological activation of AMPK with 5"-aminoimidazole-4-carboxamide riboside (AICAR) or resveratrol also markedly increases PGC-1alpha and NRF-1 mRNA levels in neuron cultures.	acadesine	51-91	PPARG coactivator 1 alpha	Rattus norvegicus	139-149	
20438809-7	2010	Similarly, pharmacological activation of AMPK with 5"-aminoimidazole-4-carboxamide riboside (AICAR) or resveratrol also markedly increases PGC-1alpha and NRF-1 mRNA levels in neuron cultures.	acadesine	93-98	PPARG coactivator 1 alpha	Rattus norvegicus	139-149	
21700896-9	2011	An acute bout of exercise, AICAR treatment, and epinephrine injections increased the mRNA levels of PGC-1alpha, COXIV, and lipin1 independent of decreases in nuclear RIP140 protein.	acadesine	27-32	PPARG coactivator 1 alpha	Rattus norvegicus	100-110