PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 16760336-9 2006 Overall, the data support the conclusion that AICAR-induced AMPK activation suppresses protein synthesis through concurrent repression of mTOR signaling and activation of MAPK signaling, the combination of which modulates transient changes in the initiation and elongation phases of mRNA translation. acadesine 46-51 mitogen-activated protein kinase 3 Homo sapiens 171-175 19190259-1 2009 We demonstrated previously that, in healthy young men, 5-aminoimidazole-4-carboxamide 1-beta-d-ribofuranoside (AICAR) stimulates human muscle 2-deoxyglucose (2DG) uptake without detectable activation of muscle AMP-activated protein kinase (AMPK) but with extracellular-regulated kinase 1/2 (ERK1/2) activation. acadesine 55-109 mitogen-activated protein kinase 3 Homo sapiens 291-297