PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
1616052-10	1992	Actinomycin D blocked the inhibitory effects of TNF-alpha and TPA on SP-A and SP-B mRNA, supporting a role for posttranscriptional events in the modulation of the expression of the surfactant proteins SP-A and SP-B.	Dactinomycin	0-13	surfactant protein A1	Homo sapiens	69-73	
8460712-9	1993	Stability of SP-A mRNA, determined both by addition of actinomycin D and by label-chase experiments, was transiently decreased immediately after adding dexamethasone (t1/2 approximately 3 h).	Dactinomycin	55-68	surfactant protein A1	Homo sapiens	13-17	
1616052-10	1992	Actinomycin D blocked the inhibitory effects of TNF-alpha and TPA on SP-A and SP-B mRNA, supporting a role for posttranscriptional events in the modulation of the expression of the surfactant proteins SP-A and SP-B.	Dactinomycin	0-13	surfactant protein A1	Homo sapiens	201-205	
2249989-8	1990	SP-A and SP-B mRNA contents decreased more rapidly after treatment with TPA than after actinomycin D.	Dactinomycin	87-100	surfactant protein A1	Homo sapiens	0-4	
1653895-9	1991	After 12 h of incubation in the presence of actinomycin-D and dexamethasone at 10(-9) and 10(-7) M, the levels of SP-A mRNA were reduced by 50% and 80%, respectively, compared to those in tissue incubated with actinomycin-D alone.	Dactinomycin	44-57	surfactant protein A1	Homo sapiens	114-118	
1653895-9	1991	After 12 h of incubation in the presence of actinomycin-D and dexamethasone at 10(-9) and 10(-7) M, the levels of SP-A mRNA were reduced by 50% and 80%, respectively, compared to those in tissue incubated with actinomycin-D alone.	Dactinomycin	210-223	surfactant protein A1	Homo sapiens	114-118	
2249989-9	1990	Actinomycin D completely blocked the rapid decrease in SP-A and SP-B mRNAs caused by the phorbol ester, consistent with the concept that the inhibitory effect of TPA on the surfactant protein mRNAs required continued gene transcription and was not mediated solely by changes in SP-A or SP-B transcription.	Dactinomycin	0-13	surfactant protein A1	Homo sapiens	278-282	
2249989-9	1990	Actinomycin D completely blocked the rapid decrease in SP-A and SP-B mRNAs caused by the phorbol ester, consistent with the concept that the inhibitory effect of TPA on the surfactant protein mRNAs required continued gene transcription and was not mediated solely by changes in SP-A or SP-B transcription.	Dactinomycin	0-13	surfactant protein A1	Homo sapiens	55-59