PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
7692234-6	1993	The macromolecular synthesis inhibitors actinomycin D and cycloheximide triggered rapid cell death of FDC-P1 cells in the presence of interleukin-3, but the cells could be protected by Bcl-2.	Dactinomycin	40-53	interleukin 3	Mus musculus	134-147	
9774347-5	1998	SB202190 and wortmannin were shown to antagonize ionomycin-induced IL-3 mRNA stabilization in PB-3c cells in the presence of actinomycin D, and this effect coincided with their ability to inhibit c-jun N-terminal kinase (JNK) activation by ionomycin.	Dactinomycin	125-138	interleukin 3	Mus musculus	67-71	
14646563-2	1997	Here we show that the onset of cell death after IL-3 withdrawal can be strongly delayed by either cycloheximide or actinomycin D, indicating that de novo protein synthesis is required.	Dactinomycin	115-128	interleukin 3	Mus musculus	48-52	
8558020-5	1996	IL-3 and IGF-I efficiently promote cell survival in the presence of inhibitors of either RNA synthesis (actinomycin D) or mitosis (mitomycin C), suggesting that both ligands promote survival by a process that is largely independent of RNA synthesis.	Dactinomycin	104-117	interleukin 3	Mus musculus	0-4	
2105489-7	1990	In cells maintained in the presence of A23187 the IL-3 mRNA was stable during 3 hr of incubation with actinomycin D, whereas removal of A23187 under the same conditions resulted in rapid degradation of the mRNA.	Dactinomycin	102-115	interleukin 3	Mus musculus	50-54	
2824613-14	1987	However, both mediators act by inducing the transcription of the HDC gene and de novo synthesis of this enzyme since actinomycin D or cycloheximide abolish GM-CSF-or IL-3-induced histamine-producing cell-stimulating activity.	Dactinomycin	117-130	interleukin 3	Mus musculus	166-170