PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
16442292-1	2006	A series of analogs with nitro or serinamide substituents at the C-2"-, C-5"-, or C-6"-position of the combretastatin A-4 (CA4) B-ring was synthesized and evaluated for cytotoxic effects against heart endothelioma cells, blood flow reduction to tumors in SCID mice, and as inhibitors of tubulin polymerization.	nitro	25-30	carbonic anhydrase 4	Mus musculus	103-121	
16442292-3	2006	Several of these nitrogen-modified CA4 derivatives (both amino and nitro) demonstrate significant inhibition of tubulin assembly as well as cytotoxicity and in vivo blood flow reduction.	nitro	17-22	carbonic anhydrase 4	Mus musculus	35-38