PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
22444681-2	2012	All the compounds were capable of inhibiting the growth of E. histolytica out of which four compounds (IC(50)=0.28-1.38 muM) were found to have better efficacy than the standard drug Metronidazole (IC(50)=1.8 muM).	Metronidazole	183-196	latexin	Homo sapiens	120-123	
32234669-12	2020	However, eight, including MMV676358 and MMV028694, which demonstrated potent sub-muM IC50s against assemblage A, B and metronidazole resistant parasites (0.3 muM and 0.9 muM respectively), may represent new leads for future drug development.	Metronidazole	119-132	latexin	Homo sapiens	81-84	
28110684-5	2017	Finally, the obtained Pt-NCs@PEI are used to determine trace amount of metronidazole (MTZ) in buffer solution in showing a linear response over a concentration range of 0.25-300 muM and a low detection limit of 0.1 muM.	Metronidazole	71-84	latexin	Homo sapiens	178-181	
28110684-5	2017	Finally, the obtained Pt-NCs@PEI are used to determine trace amount of metronidazole (MTZ) in buffer solution in showing a linear response over a concentration range of 0.25-300 muM and a low detection limit of 0.1 muM.	Metronidazole	71-84	latexin	Homo sapiens	215-218	
28110684-5	2017	Finally, the obtained Pt-NCs@PEI are used to determine trace amount of metronidazole (MTZ) in buffer solution in showing a linear response over a concentration range of 0.25-300 muM and a low detection limit of 0.1 muM.	Metronidazole	86-89	latexin	Homo sapiens	178-181	
28110684-5	2017	Finally, the obtained Pt-NCs@PEI are used to determine trace amount of metronidazole (MTZ) in buffer solution in showing a linear response over a concentration range of 0.25-300 muM and a low detection limit of 0.1 muM.	Metronidazole	86-89	latexin	Homo sapiens	215-218	
23813797-4	2013	Although several cDNA-expressed P450 enzymes catalyzed 2-hydroxymetronidazole formation at a supratherapeutic concentration of metronidazole (2000 muM), at a "therapeutic concentration" of 100 muM only CYPs 2A6, 3A4, 3A5, and 3A7 catalyzed metronidazole 2-hydroxylation at rates substantially greater than control vector, and CYP2A6 catalyzed 2-hydroxymetronidazole formation at rates 6-fold higher than the next most active enzyme.	Metronidazole	64-77	latexin	Homo sapiens	147-150	
23813797-4	2013	Although several cDNA-expressed P450 enzymes catalyzed 2-hydroxymetronidazole formation at a supratherapeutic concentration of metronidazole (2000 muM), at a "therapeutic concentration" of 100 muM only CYPs 2A6, 3A4, 3A5, and 3A7 catalyzed metronidazole 2-hydroxylation at rates substantially greater than control vector, and CYP2A6 catalyzed 2-hydroxymetronidazole formation at rates 6-fold higher than the next most active enzyme.	Metronidazole	127-140	latexin	Homo sapiens	147-150	
27236016-7	2016	Several of the new compounds exhibited potent activity against G. lamblia strains, including metronidazole-resistant strains of G. lamblia (EC50 = 0.1-2.5 muM cf.	Metronidazole	93-106	latexin	Homo sapiens	155-158	
27236016-8	2016	metronidazole EC50 = 6.1-18 muM).	Metronidazole	0-13	latexin	Homo sapiens	28-31	
23597911-5	2013	The fabricated sensor shows linear response to metronidazole in the ranges of 10 nM-1 muM and 70 muM-800 muM, with a detection limit of 2.3 nM (S/N=3).	Metronidazole	47-60	latexin	Homo sapiens	86-89	
23597911-5	2013	The fabricated sensor shows linear response to metronidazole in the ranges of 10 nM-1 muM and 70 muM-800 muM, with a detection limit of 2.3 nM (S/N=3).	Metronidazole	47-60	latexin	Homo sapiens	97-100	
23597911-5	2013	The fabricated sensor shows linear response to metronidazole in the ranges of 10 nM-1 muM and 70 muM-800 muM, with a detection limit of 2.3 nM (S/N=3).	Metronidazole	47-60	latexin	Homo sapiens	97-100	
21377771-2	2011	The results showed that out of fifteen compounds, four were found to be more active against the Entamoeba histolytica; while one compound was moderatively active compared to the standard drug metronidazole (IC50=1.46 muM).	Metronidazole	192-205	latexin	Homo sapiens	217-220