PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 32234669-12 2020 However, eight, including MMV676358 and MMV028694, which demonstrated potent sub-muM IC50s against assemblage A, B and metronidazole resistant parasites (0.3 muM and 0.9 muM respectively), may represent new leads for future drug development. Metronidazole 119-132 latexin Homo sapiens 81-84 28110684-5 2017 Finally, the obtained Pt-NCs@PEI are used to determine trace amount of metronidazole (MTZ) in buffer solution in showing a linear response over a concentration range of 0.25-300 muM and a low detection limit of 0.1 muM. Metronidazole 71-84 latexin Homo sapiens 178-181 28110684-5 2017 Finally, the obtained Pt-NCs@PEI are used to determine trace amount of metronidazole (MTZ) in buffer solution in showing a linear response over a concentration range of 0.25-300 muM and a low detection limit of 0.1 muM. Metronidazole 71-84 latexin Homo sapiens 215-218 28110684-5 2017 Finally, the obtained Pt-NCs@PEI are used to determine trace amount of metronidazole (MTZ) in buffer solution in showing a linear response over a concentration range of 0.25-300 muM and a low detection limit of 0.1 muM. Metronidazole 86-89 latexin Homo sapiens 178-181 28110684-5 2017 Finally, the obtained Pt-NCs@PEI are used to determine trace amount of metronidazole (MTZ) in buffer solution in showing a linear response over a concentration range of 0.25-300 muM and a low detection limit of 0.1 muM. Metronidazole 86-89 latexin Homo sapiens 215-218 27236016-7 2016 Several of the new compounds exhibited potent activity against G. lamblia strains, including metronidazole-resistant strains of G. lamblia (EC50 = 0.1-2.5 muM cf. Metronidazole 93-106 latexin Homo sapiens 155-158 27236016-8 2016 metronidazole EC50 = 6.1-18 muM). Metronidazole 0-13 latexin Homo sapiens 28-31 23813797-4 2013 Although several cDNA-expressed P450 enzymes catalyzed 2-hydroxymetronidazole formation at a supratherapeutic concentration of metronidazole (2000 muM), at a "therapeutic concentration" of 100 muM only CYPs 2A6, 3A4, 3A5, and 3A7 catalyzed metronidazole 2-hydroxylation at rates substantially greater than control vector, and CYP2A6 catalyzed 2-hydroxymetronidazole formation at rates 6-fold higher than the next most active enzyme. Metronidazole 64-77 latexin Homo sapiens 147-150 23813797-4 2013 Although several cDNA-expressed P450 enzymes catalyzed 2-hydroxymetronidazole formation at a supratherapeutic concentration of metronidazole (2000 muM), at a "therapeutic concentration" of 100 muM only CYPs 2A6, 3A4, 3A5, and 3A7 catalyzed metronidazole 2-hydroxylation at rates substantially greater than control vector, and CYP2A6 catalyzed 2-hydroxymetronidazole formation at rates 6-fold higher than the next most active enzyme. Metronidazole 127-140 latexin Homo sapiens 147-150 23597911-5 2013 The fabricated sensor shows linear response to metronidazole in the ranges of 10 nM-1 muM and 70 muM-800 muM, with a detection limit of 2.3 nM (S/N=3). Metronidazole 47-60 latexin Homo sapiens 86-89 23597911-5 2013 The fabricated sensor shows linear response to metronidazole in the ranges of 10 nM-1 muM and 70 muM-800 muM, with a detection limit of 2.3 nM (S/N=3). Metronidazole 47-60 latexin Homo sapiens 97-100 23597911-5 2013 The fabricated sensor shows linear response to metronidazole in the ranges of 10 nM-1 muM and 70 muM-800 muM, with a detection limit of 2.3 nM (S/N=3). Metronidazole 47-60 latexin Homo sapiens 97-100 22444681-2 2012 All the compounds were capable of inhibiting the growth of E. histolytica out of which four compounds (IC(50)=0.28-1.38 muM) were found to have better efficacy than the standard drug Metronidazole (IC(50)=1.8 muM). Metronidazole 183-196 latexin Homo sapiens 120-123 21377771-2 2011 The results showed that out of fifteen compounds, four were found to be more active against the Entamoeba histolytica; while one compound was moderatively active compared to the standard drug metronidazole (IC50=1.46 muM). Metronidazole 192-205 latexin Homo sapiens 217-220