PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 23807048-6 2013 In this transgenic system, bacterial nitroreductase enzyme (NTR), which converts the prodrug metronidazole (Mtz) into a cytotoxic DNA cross-linking agent, is expressed in oligodendrocyte lineage cells under the control of the mbp and sox10 promoter. Metronidazole 108-111 myelin basic protein a Danio rerio 226-229 25527642-8 2014 Treatment of zebrafish larvae Tg(mbp:nfsB-egfp) with metronidazole (Mtz) resulted in the selective ablation of oligodendrocytes and led to demyelination, accompanied by behavioral changes, including decreased total movement distance, velocity, total movement time and fast movement time. Metronidazole 53-66 myelin basic protein a Danio rerio 33-36 25527642-8 2014 Treatment of zebrafish larvae Tg(mbp:nfsB-egfp) with metronidazole (Mtz) resulted in the selective ablation of oligodendrocytes and led to demyelination, accompanied by behavioral changes, including decreased total movement distance, velocity, total movement time and fast movement time. Metronidazole 68-71 myelin basic protein a Danio rerio 33-36 25527642-9 2014 After withdrawal of Mtz for a seven day recovery period, the expression of EGFP and MBP protein was observed again which indicates remyelination. Metronidazole 20-23 myelin basic protein a Danio rerio 84-87