PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 26498224-3 2016 To elucidate whether single-chain fragment of variable (scFv) antibody labeled with 131I isotope is a potential imaging agent for diagnosing MTC. Iodine-131 84-88 immunglobulin heavy chain variable region Homo sapiens 56-60 28393196-5 2017 The chloramine T method was used to label scFv with 131I. Iodine-131 52-56 immunglobulin heavy chain variable region Homo sapiens 42-46 28393196-10 2017 SPECT imaging revealed that 131I-scFv selectively accumulated in tumor tissue. Iodine-131 28-32 immunglobulin heavy chain variable region Homo sapiens 33-37 11161852-10 2001 In vivo, subcutaneous or intraperitoneal growth of tumor xenografts in nu/nu mice was significantly inhibited (P = 0.004) by treatment for 10 days with scFv(FRP5)-ETA or with 131I-labeled-520C9 anti-p185HER-2 radionuclide conjugate, but additive effects were not observed with combined treatment. Iodine-131 175-179 immunglobulin heavy chain variable region Homo sapiens 152-156 19647173-9 2009 Tumor uptake of radioiodine activity in athymic mice bearing MCF7-HER2 xenografts in vivo was significantly higher for the [(125)I]IB-Mal-d-GEEEK-labeled scFv-Fc DM fragment compared with that of the [(131)I]SGMIB-labeled fragment, particularly at later time points. Iodine-131 16-27 immunglobulin heavy chain variable region Homo sapiens 154-158 19647173-11 2009 However, the [(125)I]IB-Mal-d-GEEEK-labeled scFv-Fc DM fragment also exhibited considerably higher levels of radioiodine activity in liver, spleen and kidney. Iodine-131 109-120 immunglobulin heavy chain variable region Homo sapiens 44-48