PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 24224693-1 2013 After extensive synthetic efforts, we found that many structurally diverse bioisosteres could be generated via derivatizing the C-4 alkyl chain on the pyrazole ring of compound 3 (B/P = 1/33) with different electronegative groups. pyrazole 151-159 zinc finger protein 185 Mus musculus 182-190