PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 27228464-5 2017 FGFR2, TWIST1, and FGFR3 mutations were identified in children with TCS. 9-ethyl-N-(3,4,5-trimethoxyphenyl)carbazole-3-sulfonamide 68-71 fibroblast growth factor receptor 2 Homo sapiens 0-5 27228464-6 2017 All five children with a W290C mutation in FGFR2 had TCS, and most previously reported children with W290C had identification of TCS or early death. 9-ethyl-N-(3,4,5-trimethoxyphenyl)carbazole-3-sulfonamide 53-56 fibroblast growth factor receptor 2 Homo sapiens 43-48 27228464-8 2017 CONCLUSION: There is an association between TCS and syndromic craniosynostosis, and it appears to be particularly high in individuals with the W290C mutation in FGFR2. 9-ethyl-N-(3,4,5-trimethoxyphenyl)carbazole-3-sulfonamide 44-47 fibroblast growth factor receptor 2 Homo sapiens 161-166 34133757-2 2022 TCS is associated with syndromic craniosynostoses including Apert, Crouzon and Pfeiffer syndromes and FGFR2, FGFR3, and TWIST1 variants. 9-ethyl-N-(3,4,5-trimethoxyphenyl)carbazole-3-sulfonamide 0-3 fibroblast growth factor receptor 2 Homo sapiens 102-107 34133757-17 2022 Genetic testing in patients with FGFR2-related syndromic craniosynostoses may identify those at risk of TCS and facilitate early intervention. 9-ethyl-N-(3,4,5-trimethoxyphenyl)carbazole-3-sulfonamide 104-107 fibroblast growth factor receptor 2 Homo sapiens 33-38