PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
7730304-17	1995	The following conclusions can be drawn from the calculated reaction rates: (i) about half of the lactate conversion to glucose occurs via the citrate cleavage pathway, (ii) the flux through the reversal of the isocitrate dehydrogenase reaction is almost as fast as that through the citrate synthase reaction, and (iii) the flux through citrate synthase and alpha-ketoglutarate dehydrogenase is 1.6- and 3.2-fold that through pyruvate carboxylase, respectively.	Citric Acid	142-149	citrate synthase	Rattus norvegicus	282-298	
20005400-1	2009	UNLABELLED: Citrate synthase (CS) is the one of the key enzymes in the citric acid cycle and an important mitochondrial autoantigen.	Citric Acid	71-82	citrate synthase	Rattus norvegicus	12-28	
20005400-1	2009	UNLABELLED: Citrate synthase (CS) is the one of the key enzymes in the citric acid cycle and an important mitochondrial autoantigen.	Citric Acid	71-82	citrate synthase	Rattus norvegicus	30-32	
19733154-5	2009	We also observed that the activity of the mitochondrial enzyme citrate synthase from mitochondrial preparations and purified citrate synthase was significantly inhibited by D-Ser, whereas the other activities of the citric acid cycle as well as the activities of complexes I-III, II-III, II and IV of the respiratory chain, creatine kinase and Na(+),K(+)-ATPase were not affected by this D-amino acid.	Citric Acid	216-227	citrate synthase	Rattus norvegicus	63-79	
11481570-10	2001	CONCLUSIONS: BMIPP imaging correlates well with the activities of HAD and CS, suggesting that a decrease in BMIPP uptake reflects deterioration of both fatty acid metabolism and citrate cycle and shows information other than regional myocardial perfusion.	Citric Acid	178-185	citrate synthase	Rattus norvegicus	74-76	
7730304-17	1995	The following conclusions can be drawn from the calculated reaction rates: (i) about half of the lactate conversion to glucose occurs via the citrate cleavage pathway, (ii) the flux through the reversal of the isocitrate dehydrogenase reaction is almost as fast as that through the citrate synthase reaction, and (iii) the flux through citrate synthase and alpha-ketoglutarate dehydrogenase is 1.6- and 3.2-fold that through pyruvate carboxylase, respectively.	Citric Acid	142-149	citrate synthase	Rattus norvegicus	336-352	
7816745-5	1994	The age-related decrease in muscular glucose 6-phosphate, pyruvate and alanine concentrations and increase in citrate concentration were consistent with the age-related decreased hexokinase and increased citrate synthase activities.	Citric Acid	110-117	citrate synthase	Rattus norvegicus	204-220	
6588129-4	1984	The ratio between two citrate cycle enzymes, fumarase and CS, was 4- or 5-fold higher in proximal segments than in the glomerulus or thin limb areas.	Citric Acid	22-29	citrate synthase	Rattus norvegicus	58-60	
1764503-3	1991	The first procedure is based on the conversion of oxalacetate generated from pyruvate to 14C-labelled citrate in the presence of [1-14C]acetyl-CoA and citrate synthase.	Citric Acid	102-109	citrate synthase	Rattus norvegicus	151-167	
8487208-4	1993	Changes in the aerobic oxidative capacity of the stimulated muscles were judged from increases in citrate synthase activity, representing the constant-proportion enzyme group of the citric acid cycle.	Citric Acid	182-193	citrate synthase	Rattus norvegicus	98-114	
1778900-8	1991	These muscles showed marked metabolic adaptations: training increased the activity levels of enzymes involved in the citric acid cycle (citrate synthase, CS) and the beta-oxidation of fatty acids (3 hydroxyacyl CoA dehydrogenase, HAD).	Citric Acid	117-128	citrate synthase	Rattus norvegicus	136-152	
3776117-2	1986	The liver enzyme as well as the callus citrate synthase were responsible for high rate of lipogenesis (activation of ATP-citrate lyase) and for an increase in content of citric acid within the initial period of consolidation.	Citric Acid	170-181	citrate synthase	Rattus norvegicus	39-55	
680639-11	1978	Plotting the calculated free mitochondrial oxaloacetate concentration against the citrate concentration measured in the mitochondrial pellet yielded a hyperbolic saturation curve, from which an apparent Km of citrate synthase for oxaloacetate in the intact cells of 2 micron can be derived, which is comparable to the value determined with purified rat liver citrate synthase.	Citric Acid	82-89	citrate synthase	Rattus norvegicus	209-225	
5667255-2	1968	Four of the citric acid-cycle enzymes (aconitase, succinyl-CoA thiokinase, alpha-oxoglutarate dehydrogenase and succinate dehydrogenase) have closely similar low activities; two [isocitrate dehydrogenase (NAD) and citrate synthase] have intermediate activities; the remaining two (malate dehydrogenase and fumarase) have high activities.	Citric Acid	12-23	citrate synthase	Rattus norvegicus	214-230	
7266074-6	1981	While pyruvate kinase and those mitochondrial enzymes lying between citrate formation and isocitrate oxidation (citrate synthase, NADP+-and NAD+-isocitrate dehydrogenases) decline to some degree, mitochondrial succinate dehydrogenase and NAD+-malate dehydrogenase activities increase over the same period.	Citric Acid	68-75	citrate synthase	Rattus norvegicus	112-128	
4725035-7	1973	The observed rates of H(14)CO(3) (-) fixation and citrate formation correlated with the measured activities of pyruvate carboxylase and citrate synthase in the mitochondria.	Citric Acid	50-57	citrate synthase	Rattus norvegicus	136-152	
5650365-12	1968	The effects of starvation and diabetes on the citrate and acetyl-CoA contents are discussed in relation to control of gluconeogenesis, fatty acid synthesis and the activity of citrate synthase.	Citric Acid	46-53	citrate synthase	Rattus norvegicus	176-192