PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 16286459-3 2006 ADAMTS13 activity in citrate-anticoagulated plasma was enhanced approximately 2-fold by zinc ions, approximately 3-fold by calcium ions, and approximately 6-fold by both ions, suggesting cooperative activation. Citric Acid 21-28 ADAM metallopeptidase with thrombospondin type 1 motif 13 Homo sapiens 0-8 16286459-5 2006 Barium ions stimulated ADAMTS13 activity in citrated plasma but not in citrate-free plasma. Citric Acid 44-51 ADAM metallopeptidase with thrombospondin type 1 motif 13 Homo sapiens 23-31 16286459-6 2006 Therefore, the stimulation by barium ions of ADAMTS13 in citrated plasma appears to reflect the release of chelated calcium and zinc ions from complexes with citrate. Citric Acid 57-64 ADAM metallopeptidase with thrombospondin type 1 motif 13 Homo sapiens 45-53 31006963-9 2019 No ADAMTS13 activity decrease was seen in heparinized plasma, but the addition of citrate again caused ADAMTS13 instability at 37 C. Scavenging of citrate by the addition of Ca2+ or Zn2+ prior to but not postincubation prevented the activity decrease of the enzyme. Citric Acid 82-89 ADAM metallopeptidase with thrombospondin type 1 motif 13 Homo sapiens 103-111 31006963-9 2019 No ADAMTS13 activity decrease was seen in heparinized plasma, but the addition of citrate again caused ADAMTS13 instability at 37 C. Scavenging of citrate by the addition of Ca2+ or Zn2+ prior to but not postincubation prevented the activity decrease of the enzyme. Citric Acid 147-154 ADAM metallopeptidase with thrombospondin type 1 motif 13 Homo sapiens 103-111 23773695-6 2013 RESULTS: Serum and plasma anticoagulated with citrate or heparin had equivalent ADAMTS13 activity with FRETS-rVWF71. Citric Acid 46-53 ADAM metallopeptidase with thrombospondin type 1 motif 13 Homo sapiens 80-88