PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
26863933-5	2016	Within the cytosol, citrate is readily metabolised by ATP-citrate lyase into acetyl-CoA - the metabolic precursor of endogenously produced lipids and cholesterol.	Citric Acid	20-27	ATP citrate lyase	Mus musculus	54-71	
30150300-11	2018	Cytosolic citrate is converted back to acetyl-CoA by ATP citrate lyase (ACLY).	Citric Acid	10-17	ATP citrate lyase	Mus musculus	53-70	
30150300-11	2018	Cytosolic citrate is converted back to acetyl-CoA by ATP citrate lyase (ACLY).	Citric Acid	10-17	ATP citrate lyase	Mus musculus	72-76	
24469453-6	2014	ACLY produces cytosolic acetyl-CoA from mitochondrially derived citrate.	Citric Acid	64-71	ATP citrate lyase	Mus musculus	0-4	
35203088-3	2022	AT-1 overexpressing neurons maintain the cytosolic pool of acetyl-CoA by upregulation of SLC25A1, the mitochondrial citrate/malate antiporter and ATP citrate lyase, which converts cytosolic citrate into acetyl-CoA.	Citric Acid	190-197	ATP citrate lyase	Mus musculus	146-163	
23473032-4	2013	Feeding VHL-deficient RCC cells with acetate or citrate or knocking down PDK-1 and ACLY restored citrate levels and suppressed RC.	Citric Acid	97-104	ATP citrate lyase	Mus musculus	83-87	
20488800-1	2010	ATP-citrate lyase (ACL) is a key lipogenic enzyme that converts citrate in the cytoplasm to acetyl-CoA, the initial precursor that yields malonyl-CoA for fatty acid biosynthesis.	Citric Acid	4-11	ATP citrate lyase	Mus musculus	19-22	
20488800-2	2010	As cytosolic citrate is derived from the tricarboxylic acid cycle in the mitochondrion, ACL catalyzes a critical reaction linking cellular glucose catabolism and lipid synthesis.	Citric Acid	13-20	ATP citrate lyase	Mus musculus	88-91	
19177596-3	2009	ATP-citrate lyase (ACL) is a lipogenic enzyme that catalyzes the critical reaction linking cellular glucose catabolism and lipogenesis, converting cytosolic citrate to acetyl-coenzyme A (CoA).	Citric Acid	4-11	ATP citrate lyase	Mus musculus	19-22	
32819574-5	2020	Finally, we turned our attention to inflammatory mediators derived from the cleavage of citrate catalyzed by ACLY: prostaglandin E2, nitric oxide and reactive oxygen species.	Citric Acid	88-95	ATP citrate lyase	Mus musculus	109-113	
32214246-3	2020	The ATP citrate lyase (ACLY) enzyme cleaves cytosolic citrate to generate acetyl-CoA, and is upregulated after consumption of carbohydrates7.	Citric Acid	8-15	ATP citrate lyase	Mus musculus	23-27	
31675964-10	2019	We investigated ATP citrate lyase (ACLY) because it cleaves citrate into oxaloacetate and acetyl CoA.	Citric Acid	20-27	ATP citrate lyase	Mus musculus	35-39