PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
30828001-3	2019	Following our previous studies regarding the synthesis of (+)-spectaline, herein we report the first convergent synthesis of (-)-iso-6-spectaline using a cross-metathesis under thermal conditions where the cis-2,6-disubstituted piperidin-3-ol scaffold is condensed with a long alkyl chain containing a terminal olefin.	Alkenes	311-317	suppressor of cytokine signaling 2	Homo sapiens	206-211	
22352383-0	2012	Stereoselective synthesis of cis-2,5-disubstituted pyrrolidines via Wacker-type aerobic oxidative cyclization of alkenes with tert-butanesulfinamide nucleophiles.	Alkenes	113-120	suppressor of cytokine signaling 2	Homo sapiens	29-34	
25826004-2	2015	The mild reaction conditions and high degree of functional group compatibility as demonstrated with substrates bearing heterocycles, olefins, and substituted aromatic groups, renders this technique highly valuable for the synthesis of a variety of cis-2,3-disubstituted indolines in high yield and enantioeselectivity.	Alkenes	133-140	suppressor of cytokine signaling 2	Homo sapiens	248-253	
14604356-1	2003	A new strategy for the facile synthesis of azabicyclo[m.n.1]alkenes (m = 3-5; n = 3, 2) has been developed that involves the ring-closing metathesis (RCM) reaction of cis-2,6-dialkenyl-N-acyl piperidine derivatives.	Alkenes	60-67	suppressor of cytokine signaling 2	Homo sapiens	167-172	
21391709-3	2011	To obtain the desired precursor (2S,5R)-2-allyl-5-vinylpyrrolidine for RCM reaction, we developed a general and practical method for the preparation of enantiopure cis-2,5-disubstituted pyrrolidines bearing alkene- and/or alkyne-containing substituents.	Alkenes	207-213	suppressor of cytokine signaling 2	Homo sapiens	164-169	
16833827-1	2005	cis-2,3-Dimethylaziridine reacts with difluoroamine to give the corresponding alkene and nitrogen with retention of configuration.	Alkenes	78-84	suppressor of cytokine signaling 2	Homo sapiens	0-5	
33183714-7	2021	O3 formation analysis showed that reactive alkenes such as isoprene and cis-2-butene contributed most to O3 formation.	Alkenes	43-50	suppressor of cytokine signaling 2	Homo sapiens	72-77	
33527952-1	2021	The Cu(i)-catalyzed ring-opening cross-coupling of an oxabicyclic olefin with an organoboron reagent provides access to cis-2-aryl-1,2-dihydronaphthalen-1-ol derivatives, in contrast to the exclusive trans-selectivity in related Cu-catalyzed reactions with Grignard reagents.	Alkenes	66-72	suppressor of cytokine signaling 2	Homo sapiens	120-125