PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
33803289-8	2021	The DMF treatment was also associated with increased expressions of cell-adhesion molecules (VCAM-1, ICAM-1) and no changes in HLA-DR, CD68, GFAP, NFL, or synaptic proteins.	Dimethyl Fumarate	4-7	intercellular adhesion molecule 1	Homo sapiens	101-107	
7913702-0	1994	IL-1 alpha-induced expression of ICAM-1 on cultured hyperproliferative keratinocytes: suppression by antipsoriatic dimethyl-fumarate.	Dimethyl Fumarate	115-132	intercellular adhesion molecule 1	Homo sapiens	33-39	
29075657-7	2017	After 12 months, DMF induced a decreased frequency of alphaLhighCD4+ T cells combined with reduced binding to ICAM-1.	Dimethyl Fumarate	17-20	intercellular adhesion molecule 1	Homo sapiens	110-116	
32645629-10	2020	DMF inhibited the expression of TF and ICAM-1 induced by OGD/R, which we demonstrated to be mediated through the Egr-1 signaling pathway, as silencing of Egr-1 suppressed the expression of TF and ICAM-1.	Dimethyl Fumarate	0-3	intercellular adhesion molecule 1	Homo sapiens	39-45	
32645629-10	2020	DMF inhibited the expression of TF and ICAM-1 induced by OGD/R, which we demonstrated to be mediated through the Egr-1 signaling pathway, as silencing of Egr-1 suppressed the expression of TF and ICAM-1.	Dimethyl Fumarate	0-3	intercellular adhesion molecule 1	Homo sapiens	196-202	
26690241-8	2016	DMF [30 and 100mg/kg] also caused a substantial reduction in the degree of colon injury, in the rise in myeloperoxidase [MPO] activity, and in the increase in tumour necrosis factor [TNF]-alpha expression, as well as in the up-regulation of ICAM-1 caused by DNBS in the colon.	Dimethyl Fumarate	0-3	intercellular adhesion molecule 1	Homo sapiens	241-247	
21995308-3	2011	As detected both on mRNA and protein levels, dimethylfumarate effected a profound reduction of TNFalpha-induced expression of E-selectin (CD62E), ICAM-1 (CD54) and VCAM-1 (CD106) on two different endothelial cell populations in a concentration-dependent manner.	Dimethyl Fumarate	45-61	intercellular adhesion molecule 1	Homo sapiens	146-152	
21995308-3	2011	As detected both on mRNA and protein levels, dimethylfumarate effected a profound reduction of TNFalpha-induced expression of E-selectin (CD62E), ICAM-1 (CD54) and VCAM-1 (CD106) on two different endothelial cell populations in a concentration-dependent manner.	Dimethyl Fumarate	45-61	intercellular adhesion molecule 1	Homo sapiens	154-158	
9649687-0	1998	The antipsoriatic dimethyl-fumarate suppresses interferon-gamma -induced ICAM-1 and HLA-DR expression on hyperproliferative keratinocytes.	Dimethyl Fumarate	18-35	intercellular adhesion molecule 1	Homo sapiens	73-79	
9649687-3	1998	The study focused on the effect of fumaric acid, dimethyl-fumarate, Zn-, Ca- and Mg-monoethyl-fumarate on the interferon-gamma (IFN-gamma)-induced expression of ICAM-1 and HLA-DR molecules on keratinocytes.	Dimethyl Fumarate	49-66	intercellular adhesion molecule 1	Homo sapiens	161-167	
9649687-8	1998	In the quantitative evaluation, dimethyl-fumarate significantly (p</=0.05) suppressed the expression of ICAM-1 (84%) and HLA-DR (67%) on HaCaT keratinocytes at a subtoxic concentration of 4.0 microM as compared to untreated controls (100%).	Dimethyl Fumarate	32-49	intercellular adhesion molecule 1	Homo sapiens	107-113	
9649687-10	1998	Thus, there is experimental evidence that dimethyl-fumarate may exert its antipsoriatic effect not only as an antiproliferative agent but also by down-regulation of ICAM-1 and HLA-DR molecules on hyperproliferative keratinocytes.	Dimethyl Fumarate	42-59	intercellular adhesion molecule 1	Homo sapiens	165-171	
9168952-0	1997	Dimethylfumarate is an inhibitor of cytokine-induced E-selectin, VCAM-1, and ICAM-1 expression in human endothelial cells.	Dimethyl Fumarate	0-16	intercellular adhesion molecule 1	Homo sapiens	77-83	
9168952-3	1997	Dimethylfumarate inhibited ICAM-1, VCAM-1, and E-selectin expression and reduced adhesion of U937 cells to stimulated HUVEC.	Dimethyl Fumarate	0-16	intercellular adhesion molecule 1	Homo sapiens	27-33