PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 34429340-1 2021 BACKGROUND AND OBJECTIVE: To study whether dimethyl fumarate is superior to placebo in decreasing CSF concentrations of neurofilament light chain (NFL) in patients with primary progressive MS (PPMS). Dimethyl Fumarate 43-60 neurofilament light chain Homo sapiens 147-150 31611264-7 2019 After 12 months of DMF treatment, NFL concentration decreased by 73%, 69% and 55% in the CSF, serum and plasma (p<0.0001, respectively). Dimethyl Fumarate 19-22 neurofilament light chain Homo sapiens 34-37