PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
31121086-10	2020	Hemin but not DMF caused a significant increase in intestinal HO-1 protein expression and co-administration of the HO-1 inhibitor chromium mesoporphyrin abolished the protective effects of hemin on POI; DMF reduced the IM-induced activation of NF-kappaB and ERK 1/2.	Dimethyl Fumarate	203-206	nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105	Mus musculus	244-253	
28006954-0	2017	The Neuroprotective Effect of Dimethyl Fumarate in an MPTP-Mouse Model of Parkinson"s Disease: Involvement of Reactive Oxygen Species/Nuclear Factor-kappaB/Nuclear Transcription Factor Related to NF-E2.	Dimethyl Fumarate	30-47	nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105	Mus musculus	134-155	
29361881-7	2018	Also, regulating the NF-kappaB pathway, DMF treatment decreased the severity of inflammation through a modulation of neuronal nitric oxide synthase, interleukin 1, tumor necrosis factor, cyclooxygenase 2, and myeloperoxidase activity, reducing ionized calcium-binding adapter molecule 1 and glial fibrillary acidic protein expression.	Dimethyl Fumarate	40-43	nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105	Mus musculus	21-30	
28006954-2	2017	The aim of the present study was to investigate a role for nuclear factor-kappaB (NF-kappaB)/Nrf-2 in the neurotherapeutic action of dimethyl fumarate (DMF) in a mouse model of PD and in vitro in SHSY-5Y cells.	Dimethyl Fumarate	133-150	nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105	Mus musculus	59-80	
28006954-2	2017	The aim of the present study was to investigate a role for nuclear factor-kappaB (NF-kappaB)/Nrf-2 in the neurotherapeutic action of dimethyl fumarate (DMF) in a mouse model of PD and in vitro in SHSY-5Y cells.	Dimethyl Fumarate	133-150	nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105	Mus musculus	82-91	
28006954-2	2017	The aim of the present study was to investigate a role for nuclear factor-kappaB (NF-kappaB)/Nrf-2 in the neurotherapeutic action of dimethyl fumarate (DMF) in a mouse model of PD and in vitro in SHSY-5Y cells.	Dimethyl Fumarate	152-155	nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105	Mus musculus	59-80	
28006954-2	2017	The aim of the present study was to investigate a role for nuclear factor-kappaB (NF-kappaB)/Nrf-2 in the neurotherapeutic action of dimethyl fumarate (DMF) in a mouse model of PD and in vitro in SHSY-5Y cells.	Dimethyl Fumarate	152-155	nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105	Mus musculus	82-91	
34332979-7	2021	Additionally, the anti-inflammatory activity was observed for the DMF by inhibiting the nuclear factor kappa B (NF-kappaB) level.	Dimethyl Fumarate	66-69	nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105	Mus musculus	88-110	
34332979-7	2021	Additionally, the anti-inflammatory activity was observed for the DMF by inhibiting the nuclear factor kappa B (NF-kappaB) level.	Dimethyl Fumarate	66-69	nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105	Mus musculus	112-121	
34332979-8	2021	DMF reduces the development of NAFLD induced by HFD in mice through the modulation of transcription factors Nrf2, SREBP-1c and NF-kappaB.	Dimethyl Fumarate	0-3	nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105	Mus musculus	127-136	
34772431-11	2021	The protein expressions of p-NF-kappaB/NF-kappaB and p-IKBalpha/IKBalpha was also suppressed by DMF in ALI mice.	Dimethyl Fumarate	96-99	nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105	Mus musculus	29-38	
34772431-11	2021	The protein expressions of p-NF-kappaB/NF-kappaB and p-IKBalpha/IKBalpha was also suppressed by DMF in ALI mice.	Dimethyl Fumarate	96-99	nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105	Mus musculus	39-48	
34858398-9	2021	Here we demonstrated that DMF ameliorated LPS and ATP-induced NLRP3 inflammasome activation by reducing IL-1beta, IL-18, caspase-1, and NLRP3 levels, reactive oxygen species formation and damage, and inhibiting pyroptotic cell death in N9 murine microglia via Nrf2/NF-kappaB pathways.	Dimethyl Fumarate	26-29	nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105	Mus musculus	265-274	
34332979-0	2021	Dimethyl fumarate reduces oxidative stress, inflammation and fat deposition by modulation of Nrf2, SREBP-1c and NF-kappaB signaling in HFD fed mice.	Dimethyl Fumarate	0-17	nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105	Mus musculus	112-121