PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 28006954-0 2017 The Neuroprotective Effect of Dimethyl Fumarate in an MPTP-Mouse Model of Parkinson"s Disease: Involvement of Reactive Oxygen Species/Nuclear Factor-kappaB/Nuclear Transcription Factor Related to NF-E2. Dimethyl Fumarate 30-47 nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 Mus musculus 134-155 29361881-7 2018 Also, regulating the NF-kappaB pathway, DMF treatment decreased the severity of inflammation through a modulation of neuronal nitric oxide synthase, interleukin 1, tumor necrosis factor, cyclooxygenase 2, and myeloperoxidase activity, reducing ionized calcium-binding adapter molecule 1 and glial fibrillary acidic protein expression. Dimethyl Fumarate 40-43 nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 Mus musculus 21-30 28006954-2 2017 The aim of the present study was to investigate a role for nuclear factor-kappaB (NF-kappaB)/Nrf-2 in the neurotherapeutic action of dimethyl fumarate (DMF) in a mouse model of PD and in vitro in SHSY-5Y cells. Dimethyl Fumarate 133-150 nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 Mus musculus 59-80 28006954-2 2017 The aim of the present study was to investigate a role for nuclear factor-kappaB (NF-kappaB)/Nrf-2 in the neurotherapeutic action of dimethyl fumarate (DMF) in a mouse model of PD and in vitro in SHSY-5Y cells. Dimethyl Fumarate 133-150 nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 Mus musculus 82-91 28006954-2 2017 The aim of the present study was to investigate a role for nuclear factor-kappaB (NF-kappaB)/Nrf-2 in the neurotherapeutic action of dimethyl fumarate (DMF) in a mouse model of PD and in vitro in SHSY-5Y cells. Dimethyl Fumarate 152-155 nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 Mus musculus 59-80 28006954-2 2017 The aim of the present study was to investigate a role for nuclear factor-kappaB (NF-kappaB)/Nrf-2 in the neurotherapeutic action of dimethyl fumarate (DMF) in a mouse model of PD and in vitro in SHSY-5Y cells. Dimethyl Fumarate 152-155 nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 Mus musculus 82-91 34332979-0 2021 Dimethyl fumarate reduces oxidative stress, inflammation and fat deposition by modulation of Nrf2, SREBP-1c and NF-kappaB signaling in HFD fed mice. Dimethyl Fumarate 0-17 nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 Mus musculus 112-121 34772431-11 2021 The protein expressions of p-NF-kappaB/NF-kappaB and p-IKBalpha/IKBalpha was also suppressed by DMF in ALI mice. Dimethyl Fumarate 96-99 nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 Mus musculus 29-38 34772431-11 2021 The protein expressions of p-NF-kappaB/NF-kappaB and p-IKBalpha/IKBalpha was also suppressed by DMF in ALI mice. Dimethyl Fumarate 96-99 nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 Mus musculus 39-48 34858398-9 2021 Here we demonstrated that DMF ameliorated LPS and ATP-induced NLRP3 inflammasome activation by reducing IL-1beta, IL-18, caspase-1, and NLRP3 levels, reactive oxygen species formation and damage, and inhibiting pyroptotic cell death in N9 murine microglia via Nrf2/NF-kappaB pathways. Dimethyl Fumarate 26-29 nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 Mus musculus 265-274 34332979-7 2021 Additionally, the anti-inflammatory activity was observed for the DMF by inhibiting the nuclear factor kappa B (NF-kappaB) level. Dimethyl Fumarate 66-69 nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 Mus musculus 88-110 34332979-7 2021 Additionally, the anti-inflammatory activity was observed for the DMF by inhibiting the nuclear factor kappa B (NF-kappaB) level. Dimethyl Fumarate 66-69 nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 Mus musculus 112-121 34332979-8 2021 DMF reduces the development of NAFLD induced by HFD in mice through the modulation of transcription factors Nrf2, SREBP-1c and NF-kappaB. Dimethyl Fumarate 0-3 nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 Mus musculus 127-136 31121086-10 2020 Hemin but not DMF caused a significant increase in intestinal HO-1 protein expression and co-administration of the HO-1 inhibitor chromium mesoporphyrin abolished the protective effects of hemin on POI; DMF reduced the IM-induced activation of NF-kappaB and ERK 1/2. Dimethyl Fumarate 203-206 nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 Mus musculus 244-253