PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 27645339-9 2016 The risk of disability progression (3-month) was reduced by 19-28% with interferon-beta products, glatiramer acetate, fingolimod and teriflunomide, by 38-45% for pegylated interferon-beta, dimethyl fumarate and natalizumab and by 68% with alemtuzumab. Dimethyl Fumarate 189-206 interferon beta 1 Homo sapiens 72-87 28906152-11 2017 Among treatment-naive patients, those receiving DMF had 2.4-times the risk (HR = 2.439, 95% CI = 1.007-5.917, p = .0483) of experiencing a discontinuation than patients receiving sc IFN beta-1a. Dimethyl Fumarate 48-51 interferon beta 1 Homo sapiens 182-190 28906152-12 2017 Non-persistent patients receiving DMF had 2.3-times the risk (HR = 2.311, 95% CI = 1.350-3.958, p = .0023) of experiencing an adverse event at a given time point than patients prescribed sc IFN beta-1a. Dimethyl Fumarate 34-37 interferon beta 1 Homo sapiens 190-198 28751099-2 2017 Post hoc analyses of integrated data from DEFINE/CONFIRM were conducted to evaluate the effect of DMF in patients previously treated with interferon (IFN) beta. Dimethyl Fumarate 98-101 interferon beta 1 Homo sapiens 138-159 28211024-7 2017 Compared with DMF, the adjusted IRR (95% CI) for relapse in the year after initiating therapy was 1.27 (1.10-1.46) for IFNbeta, 1.34 (1.17-1.53) for GA, 1.23 (1.05-1.45) for teriflunomide, and 1.03 (0.88-1.21) for fingolimod. Dimethyl Fumarate 14-17 interferon beta 1 Homo sapiens 119-126 24759080-4 2014 RECENT FINDINGS: Recent large placebo-controlled trials in relapsing-remitting multiple sclerosis have shown efficacy of new oral disease-modifying drugs, teriflunomide and dimethyl fumarate, with similar or better efficacy than the injectable disease-modifying drugs, IFN-beta and glatiramer acetate. Dimethyl Fumarate 173-190 interferon beta 1 Homo sapiens 269-277 27252601-0 2016 Safety and Tolerability of Delayed-Release Dimethyl Fumarate Administered with Interferon Beta or Glatiramer Acetate in Relapsing-Remitting Multiple Sclerosis. Dimethyl Fumarate 43-60 interferon beta 1 Homo sapiens 79-94 27252601-2 2016 The objective of this study was to explore the safety and tolerability of DMF when administered with interferon beta (IFNbeta) or glatiramer acetate (GA). Dimethyl Fumarate 74-77 interferon beta 1 Homo sapiens 101-116 25182864-2 2014 Following recent regulatory approvals in the USA and European Union, IFN beta-1b is now one of the seven disease-modifying therapies [intramuscular IFN beta-1a; subcutaneous (SC) IFN beta-1a; IFN beta-1b SC; glatiramer acetate SC; oral dimethyl fumarate; oral teriflunomide; and intravenous alemtuzumab] indicated for first-line use in relapsing-remitting MS. Dimethyl Fumarate 236-253 interferon beta 1 Homo sapiens 69-77