PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 20518072-3 2010 ENOX2 has been proposed as the cellular target for various quinone site inhibitors that demonstrate anticancer activity such as the green tea constituent epigallocatechin-3-gallate (EGCg) and the isoflavone phenoxodiol (PXD). quinone 59-66 ecto-NOX disulfide-thiol exchanger 2 Homo sapiens 0-5 12565167-4 2003 A tumor-associated NOX (tNOX) is unregulated, refractory to hormones and growth factors and responds to quinone-site inhibitors. quinone 104-111 ecto-NOX disulfide-thiol exchanger 2 Homo sapiens 24-28 11888291-7 2002 Functional motifs identified by site-directed mutagenesis within the C-terminal portion of the tNOX protein corresponding to the processed plasma membrane-associated form include quinone (capsaicin), copper and adenine nucleotide binding domains, and two cysteines essential for catalytic activity. quinone 179-186 ecto-NOX disulfide-thiol exchanger 2 Homo sapiens 95-99 17379941-5 2006 Because the drug-inhibited ECTO-NOX protein, tNOX was utilized, the enlargement was inhibited by capsaicin, a quinone site tNOX inhibitor specific for tNOX. quinone 110-117 ecto-NOX disulfide-thiol exchanger 2 Homo sapiens 45-49 17379941-5 2006 Because the drug-inhibited ECTO-NOX protein, tNOX was utilized, the enlargement was inhibited by capsaicin, a quinone site tNOX inhibitor specific for tNOX. quinone 110-117 ecto-NOX disulfide-thiol exchanger 2 Homo sapiens 123-127 17379941-5 2006 Because the drug-inhibited ECTO-NOX protein, tNOX was utilized, the enlargement was inhibited by capsaicin, a quinone site tNOX inhibitor specific for tNOX. quinone 110-117 ecto-NOX disulfide-thiol exchanger 2 Homo sapiens 123-127