PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 17161514-4 2007 Considering that many toxic effects of AhR ligands are dependent on AhR activation, our first objective was to determine if benzene, hydroquinone (HQ) or benzoquinone (BQ) could activate the AhR. quinone 154-166 aryl-hydrocarbon receptor Mus musculus 39-42 17161514-4 2007 Considering that many toxic effects of AhR ligands are dependent on AhR activation, our first objective was to determine if benzene, hydroquinone (HQ) or benzoquinone (BQ) could activate the AhR. quinone 154-166 aryl-hydrocarbon receptor Mus musculus 68-71 17161514-4 2007 Considering that many toxic effects of AhR ligands are dependent on AhR activation, our first objective was to determine if benzene, hydroquinone (HQ) or benzoquinone (BQ) could activate the AhR. quinone 154-166 aryl-hydrocarbon receptor Mus musculus 68-71 17161514-4 2007 Considering that many toxic effects of AhR ligands are dependent on AhR activation, our first objective was to determine if benzene, hydroquinone (HQ) or benzoquinone (BQ) could activate the AhR. quinone 168-170 aryl-hydrocarbon receptor Mus musculus 39-42 17161514-5 2007 Secondly, because the AhR regulates a number of enzymes involved in oxidative stress pathways, we sought to determine if the AhR had a role in HQ and BQ induced production of reactive oxygen species (ROS). quinone 150-152 aryl-hydrocarbon receptor Mus musculus 125-128 17161514-7 2007 Immunofluorescence staining showed cytosolic localization of the AhR after 2h incubations with benzene, HQ or BQ. quinone 110-112 aryl-hydrocarbon receptor Mus musculus 65-68 17161514-9 2007 Dichlorodihydrofluorescein staining of cells exposed to benzene, HQ or BQ revealed that the presence of the AhR did not affect BQ and HQ induced ROS production. quinone 71-73 aryl-hydrocarbon receptor Mus musculus 108-111 26558468-3 2015 However, quinone species produced from mono- and bi-aromatic hydrocarbons could potentially cause AhR activation. quinone 9-16 aryl-hydrocarbon receptor Mus musculus 98-101