PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 32816304-6 2021 In vivo, TNF-alpha accelerated the process of IVDD and suppressed SHOX2 expression; compared to the DP group, WDS was significantly increased in TNF-alpha intradiscal injection group at 2-6 weeks after puncture(p<0.05); In NP cells, TNF-alpha negatively affected the IVDD-associated SHOX2 suppression. ivdd 46-50 tumor necrosis factor Canis lupus familiaris 9-18 32816304-6 2021 In vivo, TNF-alpha accelerated the process of IVDD and suppressed SHOX2 expression; compared to the DP group, WDS was significantly increased in TNF-alpha intradiscal injection group at 2-6 weeks after puncture(p<0.05); In NP cells, TNF-alpha negatively affected the IVDD-associated SHOX2 suppression. ivdd 267-271 tumor necrosis factor Canis lupus familiaris 9-18 32816304-6 2021 In vivo, TNF-alpha accelerated the process of IVDD and suppressed SHOX2 expression; compared to the DP group, WDS was significantly increased in TNF-alpha intradiscal injection group at 2-6 weeks after puncture(p<0.05); In NP cells, TNF-alpha negatively affected the IVDD-associated SHOX2 suppression. ivdd 267-271 tumor necrosis factor Canis lupus familiaris 145-154 32816304-6 2021 In vivo, TNF-alpha accelerated the process of IVDD and suppressed SHOX2 expression; compared to the DP group, WDS was significantly increased in TNF-alpha intradiscal injection group at 2-6 weeks after puncture(p<0.05); In NP cells, TNF-alpha negatively affected the IVDD-associated SHOX2 suppression. ivdd 267-271 tumor necrosis factor Canis lupus familiaris 145-154 32816304-7 2021 While TNF-alpha promotes IVDD through activation of both MAPK and NF-kappaB signaling, it seemed that only NF-kappaB signaling controlled the TNF-alpha-mediated SHOX2 suppression that is associated with IVDD. ivdd 25-29 tumor necrosis factor Canis lupus familiaris 6-15 32816304-7 2021 While TNF-alpha promotes IVDD through activation of both MAPK and NF-kappaB signaling, it seemed that only NF-kappaB signaling controlled the TNF-alpha-mediated SHOX2 suppression that is associated with IVDD. ivdd 203-207 tumor necrosis factor Canis lupus familiaris 142-151