PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 31677062-3 2020 We postulated that febuxostat, a novel xanthine oxidase inhibitor, could suppress the ER stress through upregulation of SIRT1 (silent mating type information regulation 2 homolog 1)-AMPK (AMP activated protein kinase)-HO-1 (heme oxygenase-1)/thioredoxin expression. febuxostat 19-29 thioredoxin 1 Mus musculus 242-253