PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 31754153-3 2019 In this study, we report that febuxostat, an inhibitor of XOR, suppressed NLRP3 inflammasome-mediated IL-1beta secretion and cell death by two mechanisms: in a mitochondrial ROS (mitoROS)-dependent and mitoROS-independent manner. febuxostat 30-40 interleukin 1 beta Homo sapiens 102-110