PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 34049969-6 2021 Importantly, plasma IL-6 and C-reactive protein (CRP) levels positively correlated with mitochondrial mass and negatively correlated with fatty acid uptake in T cells from COVID-19 patients. Fatty Acids 138-148 C-reactive protein Homo sapiens 29-47 7338519-5 1981 Agglutination of liposomes caused by CRP was dependent on the fatty acid composition of phosphatidylcholine, cholesterol content and temperature. Fatty Acids 62-72 C-reactive protein Homo sapiens 37-40 34049969-6 2021 Importantly, plasma IL-6 and C-reactive protein (CRP) levels positively correlated with mitochondrial mass and negatively correlated with fatty acid uptake in T cells from COVID-19 patients. Fatty Acids 138-148 C-reactive protein Homo sapiens 49-52 32559180-5 2020 Interestingly, metabolite levels in these pathways correlated with clinical laboratory markers of inflammation (i.e., IL-6 and C-reactive protein) and renal function (i.e., blood urea nitrogen).CONCLUSIONIn conclusion, this initial observational study identified amino acid and fatty acid metabolism as correlates of COVID-19, providing mechanistic insights, potential markers of clinical severity, and potential therapeutic targets.FUNDINGBoettcher Foundation Webb-Waring Biomedical Research Award; National Institute of General and Medical Sciences, NIH; and National Heart, Lung, and Blood Institute, NIH. Fatty Acids 278-288 C-reactive protein Homo sapiens 127-145 29107850-6 2018 Regression models found several significant fatty acids at which the strength of the parameter beta for each fatty acid on selected markers of C-reactive protein, malondialdehyde, interleukin-6 and serum amyloid A was estimated. Fatty Acids 44-54 C-reactive protein Homo sapiens 143-161 29736227-4 2017 The intake of these fatty acids is related to decrease concentration of C-reactive protein (CRP), proinflammatory eicosanoids, cytokines, chemokines and other inflammation biomarkers. Fatty Acids 20-31 C-reactive protein Homo sapiens 72-90 29736227-4 2017 The intake of these fatty acids is related to decrease concentration of C-reactive protein (CRP), proinflammatory eicosanoids, cytokines, chemokines and other inflammation biomarkers. Fatty Acids 20-31 C-reactive protein Homo sapiens 92-95 28207502-0 2017 Impact of the dietary fatty acid intake on C-reactive protein levels in US adults. Fatty Acids 22-32 C-reactive protein Homo sapiens 43-61 28207502-2 2017 We assessed whether reported dietary fatty acid intake correlates with a serum high-sensitivity C-reactive protein (hs-CRP) concentration in a population-based sample of US men and women.In this cross-sectional analysis, participants were selected from the US National Health and Nutrition Examination Survey (NHANES) and restricted to those with available data on dietary intake, biochemical and anthropometric measurements from 2001 to 2010. Fatty Acids 37-47 C-reactive protein Homo sapiens 96-114 26923510-2 2016 We hypothesized that inflammatory markers interleukin (IL)-6 and C-reactive protein (CRP) mediate the associations between antioxidant and fatty acid intakes, and depression. Fatty Acids 139-149 C-reactive protein Homo sapiens 65-83 26923510-2 2016 We hypothesized that inflammatory markers interleukin (IL)-6 and C-reactive protein (CRP) mediate the associations between antioxidant and fatty acid intakes, and depression. Fatty Acids 139-149 C-reactive protein Homo sapiens 85-88 26923510-12 2016 CRP significantly mediated the relationship between total fat, saturated fat, and monounsaturated fat intakes and depression in women, and saturated fat intake and depression in men. Fatty Acids 63-76 C-reactive protein Homo sapiens 0-3 26923510-12 2016 CRP significantly mediated the relationship between total fat, saturated fat, and monounsaturated fat intakes and depression in women, and saturated fat intake and depression in men. Fatty Acids 88-101 C-reactive protein Homo sapiens 0-3 26728928-2 2016 Associations of serum CRP with FAs in different populations have not been established. Fatty Acids 31-34 C-reactive protein Homo sapiens 22-25 26728928-9 2016 Japanese Americans had CRP associations with n-3 FAs, n-6 FAs, and TFAs similar to but weaker than Whites. Fatty Acids 49-52 C-reactive protein Homo sapiens 23-26 26728928-9 2016 Japanese Americans had CRP associations with n-3 FAs, n-6 FAs, and TFAs similar to but weaker than Whites. Fatty Acids 58-61 C-reactive protein Homo sapiens 23-26 26728928-10 2016 CONCLUSIONS: With the exception of consistent inverse association of CRP with total n-6 FAs, there are considerable variations across the three populations in the associations of CRP with different FAs. Fatty Acids 88-91 C-reactive protein Homo sapiens 69-72 26456189-0 2016 Interaction of SNP in the CRP gene and plasma fatty acid profile in inflammatory pattern: A cross-sectional population-based study. Fatty Acids 46-56 C-reactive protein Homo sapiens 26-29 26456189-10 2016 CONCLUSIONS: The INF group exhibited changes in metabolic parameters that predispose this group to chronic disease, where polymorphisms in the CRP gene modulated the risk of being in the INF group depending on individual plasma fatty acid and lipid profile. Fatty Acids 228-238 C-reactive protein Homo sapiens 143-146 25393688-6 2014 Lipid intake modulated the pro-inflammatory effects of some SNPs, i.e., an increase in both saturated fatty acid and monounsaturated fatty acid intake in those homozygous for the polymorphic allele at rs2808630 was associated with a larger increase in CRP. Fatty Acids 92-112 C-reactive protein Homo sapiens 252-255 26161268-8 2015 Plasma saturated fatty acids (SFA) were positively associated with CRP (beta = 0.24; 95% CI: 0.08 to 0.40, p = 0.003) and triglycerides (beta = 0.08; 95% CI: 0.03 to 0.12, p < 0.01). Fatty Acids 7-28 C-reactive protein Homo sapiens 67-70 26161268-8 2015 Plasma saturated fatty acids (SFA) were positively associated with CRP (beta = 0.24; 95% CI: 0.08 to 0.40, p = 0.003) and triglycerides (beta = 0.08; 95% CI: 0.03 to 0.12, p < 0.01). Fatty Acids 30-33 C-reactive protein Homo sapiens 67-70 25087591-0 2014 Associations of erythrocyte membrane fatty acids with the concentrations of C-reactive protein, interleukin 1 receptor antagonist and adiponectin in 1373 men. Fatty Acids 37-48 C-reactive protein Homo sapiens 76-118 25221751-3 2014 This study was conducted to examine the association between dietary fatty acid intakes and inflammatory markers, interleukin 6 (IL-6) and high sensitivity C-reactive protein (hs-CRP), in CAD patients among Iranian population. Fatty Acids 68-78 C-reactive protein Homo sapiens 155-173 25228402-0 2014 The relationship between specific Fatty acids of serum lipids and serum high sensitivity C- reactive protein levels in morbidly obese women. Fatty Acids 34-45 C-reactive protein Homo sapiens 89-108 24561973-9 2014 On the other hand, dietary intake of saturated fatty acids showed a negative correlation with serum C-reactive protein levels (p=0.001) in males. Fatty Acids 37-58 C-reactive protein Homo sapiens 100-118 25228402-1 2014 BACKGROUND/AIMS: The fatty acid profile in plasma lipids contributes to the increase of plasma high sensitivity C-reactive protein (hsCRP), a marker of inflammation and predictor of cardiovascular risk. Fatty Acids 21-31 C-reactive protein Homo sapiens 112-130 23234408-5 2013 The switch from SAFA diet to PUFA diet produced a significant change of CRP (C-reactive protein) concentration (p<0.01) whereas similar trend of IL-18 did not reach statistical significance. Fatty Acids 16-20 C-reactive protein Homo sapiens 72-75 23594583-0 2013 Saturated fatty acids intake in relation to C-reactive protein, adiponectin, and leptin: a population-based study. Fatty Acids 0-21 C-reactive protein Homo sapiens 44-62 23234408-5 2013 The switch from SAFA diet to PUFA diet produced a significant change of CRP (C-reactive protein) concentration (p<0.01) whereas similar trend of IL-18 did not reach statistical significance. Fatty Acids 16-20 C-reactive protein Homo sapiens 77-95 22153152-0 2012 Relationship of serum fatty acid composition and desaturase activity to C-reactive protein in Japanese men and women. Fatty Acids 22-32 C-reactive protein Homo sapiens 72-90 22891522-6 2012 C-reactive protein level had a significant association with body mass index (r = 0.18), adiposity (r = 0.23), smoking (r = 0.20), carbohydrate intake (r = 0.19) and saturated fatty acid (r = 0.20). Fatty Acids 165-185 C-reactive protein Homo sapiens 0-18 22153152-1 2012 BACKGROUND: Although fatty acid composition in serum and desaturase activity, which alters serum fatty acid composition, has been associated with C-reactive protein (CRP) concentration in Western populations, no study has been carried out in non-Western populations. Fatty Acids 21-31 C-reactive protein Homo sapiens 146-164 22153152-1 2012 BACKGROUND: Although fatty acid composition in serum and desaturase activity, which alters serum fatty acid composition, has been associated with C-reactive protein (CRP) concentration in Western populations, no study has been carried out in non-Western populations. Fatty Acids 21-31 C-reactive protein Homo sapiens 166-169 22153152-1 2012 BACKGROUND: Although fatty acid composition in serum and desaturase activity, which alters serum fatty acid composition, has been associated with C-reactive protein (CRP) concentration in Western populations, no study has been carried out in non-Western populations. Fatty Acids 97-107 C-reactive protein Homo sapiens 146-164 22153152-1 2012 BACKGROUND: Although fatty acid composition in serum and desaturase activity, which alters serum fatty acid composition, has been associated with C-reactive protein (CRP) concentration in Western populations, no study has been carried out in non-Western populations. Fatty Acids 97-107 C-reactive protein Homo sapiens 166-169 22153152-2 2012 We examined the association of serum fatty acids and estimated desaturase activity with CRP concentrations in Japanese men and women. Fatty Acids 37-48 C-reactive protein Homo sapiens 88-91 20891039-1 2010 Laser correlation spectroscopy has indicated that plasma C-reactive protein (CRP) is present as a monomer and a pentamer (pentraxin); the latter is similar in physicochemical properties to apolipoproteins, the proteins that transfer fatty acids as nonpolar triglycerides to the cells in the intercellular medium. Fatty Acids 233-244 C-reactive protein Homo sapiens 57-75 20891039-1 2010 Laser correlation spectroscopy has indicated that plasma C-reactive protein (CRP) is present as a monomer and a pentamer (pentraxin); the latter is similar in physicochemical properties to apolipoproteins, the proteins that transfer fatty acids as nonpolar triglycerides to the cells in the intercellular medium. Fatty Acids 233-244 C-reactive protein Homo sapiens 77-80 19803417-3 2009 Epidemiological studies have revealed demographic and socioeconomic factors that associate with CRP concentration; these include age, sex, birth weight, ethnicity, socioeconomic status, body mass index (BMI), fiber consumption, alcohol intake, and dietary fatty acids. Fatty Acids 256-267 C-reactive protein Homo sapiens 96-99 18687433-1 2009 BACKGROUND: Fatty acid (FA) composition in serum has been associated with C-reactive protein (CRP), but associations with other markers of inflammation and endothelial function, e.g. adhesion molecules are unknown. Fatty Acids 12-22 C-reactive protein Homo sapiens 74-92 18687433-1 2009 BACKGROUND: Fatty acid (FA) composition in serum has been associated with C-reactive protein (CRP), but associations with other markers of inflammation and endothelial function, e.g. adhesion molecules are unknown. Fatty Acids 12-22 C-reactive protein Homo sapiens 94-97 20204259-0 2010 [Effect of a high saturated fatty acids load on serum concentrations of C-reactive protein, alpha1-antitrypsin, fibrinogen and alpha1-acid glycoprotein in obese women]. Fatty Acids 18-39 C-reactive protein Homo sapiens 72-90 18810827-0 2008 [Apo-E, C-reactive protein, and apolipoprotein (A) are vector proteins for transfer of fatty acids to loose connective tissue cells at the stages of inflammation syndrome and in mutations]. Fatty Acids 87-98 C-reactive protein Homo sapiens 8-26 18724426-0 2008 [C-reactive protein is a vector of fatty acid transfer to the cells that directly realize the systemic inflammatory response syndrome]. Fatty Acids 35-45 C-reactive protein Homo sapiens 1-19 18763328-0 2008 [C-reactive protein: effect of hormones, physical activity, and dietary fatty acids. Fatty Acids 72-83 C-reactive protein Homo sapiens 1-19 12370214-0 2002 Supplementation with conjugated linoleic acid causes isomer-dependent oxidative stress and elevated C-reactive protein: a potential link to fatty acid-induced insulin resistance. Fatty Acids 140-150 C-reactive protein Homo sapiens 100-118