PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
28707979-5	2018	Recent Advances: New work has begun to elucidate the roles of SIRT5 in glycolysis, tricarboxylic acid cycle, fatty acid oxidation, nitrogen metabolism, pentose phosphate pathway, antioxidant defense, and apoptosis.	Fatty Acids	109-119	sirtuin 5	Homo sapiens	62-67	
32991157-6	2020	Accumulating studies suggest that SIRT5 is involved in regulating diverse biological processes, such as reactive oxygen defense, fatty acid metabolism and apoptosis.	Fatty Acids	129-139	sirtuin 5	Homo sapiens	34-39	
31575700-4	2019	Sirtuin 5 (Sirt5), which localizes to both mitochondria and peroxisomes, reverses post-translational lysine acylation on several enzymes involved in fatty acid oxidation.	Fatty Acids	149-159	sirtuin 5	Homo sapiens	11-16	
29637793-4	2018	SIRT5 regulates protein substrates involved in glycolysis, the TCA cycle, fatty acid oxidation, electron transport chain, ketone body formation, nitrogenous waste management, and ROS detoxification, among other processes.	Fatty Acids	74-84	sirtuin 5	Homo sapiens	0-5	
25811481-1	2015	SIRT3 and SIRT5 have been shown to regulate mitochondrial fatty acid oxidation but the molecular mechanisms behind the regulation are lacking.	Fatty Acids	58-68	sirtuin 5	Homo sapiens	10-15	
25811481-2	2015	Here, we demonstrate that SIRT3 and SIRT5 both target human very long-chain acyl-CoA dehydrogenase (VLCAD), a key fatty acid oxidation enzyme.	Fatty Acids	114-124	sirtuin 5	Homo sapiens	36-41	
25811481-9	2015	Thus, SIRT3 and SIRT5 promote fatty acid oxidation by converging upon VLCAD to promote its activity and membrane localization.	Fatty Acids	30-40	sirtuin 5	Homo sapiens	16-21	
28458255-1	2017	SIRT5 is a lysine desuccinylase known to regulate mitochondrial fatty acid oxidation and the urea cycle.	Fatty Acids	64-74	sirtuin 5	Homo sapiens	0-5