PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 20811644-8 2010 The flavonoid activates PPAR response element (PPRE) while suppressing LXRalpha response element (LXRE) in human hepatocytes, translating into the induction of PPAR-regulated fatty acid oxidation genes such as CYP4A11, ACOX, UCP1 and ApoAI, and inhibition of LXRalpha-regulated lipogenesis genes, such as FAS, ABCA1, ABCG1, and HMGR. Fatty Acids 175-185 high mobility group AT-hook 1 Homo sapiens 328-332 17434141-0 2007 Fatty acid represses insulin receptor gene expression by impairing HMGA1 through protein kinase Cepsilon. Fatty Acids 0-10 high mobility group AT-hook 1 Homo sapiens 67-72 25643065-10 2015 Although further validation is needed, our results suggest that high levels of HMGA1 protein drive metabolic alterations that contribute to CRC pathogenesis through fatty acid synthesis. Fatty Acids 165-175 high mobility group AT-hook 1 Homo sapiens 79-84