PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 19127140-2 2008 Synthesized through nitric oxide, carbon monoxide, and/or natriuretic peptide-mediated guanylate cyclase stimulation and guanosine triphosphate dephosphorylation, cyclic GMP is capable of stimulating a cascade of serine/threonine kinase events, including signaling through cyclic GMP- and/or cyclic AMP-dependent protein kinases, eliciting protein kinase-independent actions such as modulation of ion channels or transporters, or undergoing hydrolytic degradation through actions of cyclic GMP-regulated phosphodiesterases. triphosphoric acid 131-143 5'-nucleotidase, cytosolic II Homo sapiens 170-173