PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 9338077-3 1998 First, the activity of ara-C depends on conversion to its lethal triphosphate derivative, ara-CTP, a process that is influenced by multiple factors, including nucleoside transport, phosphorylation, deamination, and levels of competing metabolites, particularly dCTP. triphosphoric acid 65-77 solute carrier family 25 member 1 Homo sapiens 94-97 3567973-2 1987 Studies were performed to determine if m-AMSA affected the pharmacokinetics of the active triphosphate ara-CTP in HL-60 and K562 cells in culture. triphosphoric acid 90-102 solute carrier family 25 member 1 Homo sapiens 107-110 8547650-1 1996 The effectiveness of arabinosylcytosine (ara-C) for the treatment of acute myelogenous leukemia (AML) depends on the formation of its active metabolite, the triphosphate of ara-C (ara-CTP). triphosphoric acid 157-169 solute carrier family 25 member 1 Homo sapiens 184-187 8174200-1 1994 Previous studies have demonstrated that treatment with fludarabine 4 h prior to arabinosylcytosine (ara-C) potentiates the accumulation of the active triphosphate of ara-C (ara-CTP) in leukemic lymphocytes. triphosphoric acid 150-162 solute carrier family 25 member 1 Homo sapiens 177-180