PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
25319133-8	2014	Of note, the inhibitory effects of PDN on the IL-1beta-induced expression of COX-2 and the activation of ERK-1/2 and JNK-1 in the HEI-OC1 cells were significantly diminished by RU486, a glucocorticoid receptor (GR) antagonist, suggesting that PDN exerts its inhibitory effects through GR.	Mifepristone	177-182	mitogen-activated protein kinase 8	Homo sapiens	117-122	
24597985-5	2014	Furthermore, co-treatment remarkably activated glucocorticoid receptor (GR), p38-MAPK and JNK, and all of them were canceled only by the GR inhibitor RU486, indicating GR might be an at the upstream of GR-p38-MAPK/JNK pathway.	Mifepristone	150-155	mitogen-activated protein kinase 8	Homo sapiens	90-93	
24597985-5	2014	Furthermore, co-treatment remarkably activated glucocorticoid receptor (GR), p38-MAPK and JNK, and all of them were canceled only by the GR inhibitor RU486, indicating GR might be an at the upstream of GR-p38-MAPK/JNK pathway.	Mifepristone	150-155	mitogen-activated protein kinase 8	Homo sapiens	214-217	
23624748-8	2013	RU486 increased the phosphorylation of p38 MAPK and JNK, but p38 MAPK only was associated with RU486-mediated apoptosis.	Mifepristone	0-5	mitogen-activated protein kinase 8	Homo sapiens	52-55	
12837923-7	2003	JAK1 and JNK1 were two of the genes shown by the arrays to be down-regulated in RU486-treated endometrial explants.	Mifepristone	80-85	mitogen-activated protein kinase 8	Homo sapiens	9-13	
12837923-10	2003	These results show that components of two important signalling pathways in endometrium-the JAK/STAT pathway, and the JNK pathway-are altered by RU486.	Mifepristone	144-149	mitogen-activated protein kinase 8	Homo sapiens	117-120