PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 24597985-5 2014 Furthermore, co-treatment remarkably activated glucocorticoid receptor (GR), p38-MAPK and JNK, and all of them were canceled only by the GR inhibitor RU486, indicating GR might be an at the upstream of GR-p38-MAPK/JNK pathway. Mifepristone 150-155 mitogen-activated protein kinase 8 Homo sapiens 90-93 25319133-8 2014 Of note, the inhibitory effects of PDN on the IL-1beta-induced expression of COX-2 and the activation of ERK-1/2 and JNK-1 in the HEI-OC1 cells were significantly diminished by RU486, a glucocorticoid receptor (GR) antagonist, suggesting that PDN exerts its inhibitory effects through GR. Mifepristone 177-182 mitogen-activated protein kinase 8 Homo sapiens 117-122 24597985-5 2014 Furthermore, co-treatment remarkably activated glucocorticoid receptor (GR), p38-MAPK and JNK, and all of them were canceled only by the GR inhibitor RU486, indicating GR might be an at the upstream of GR-p38-MAPK/JNK pathway. Mifepristone 150-155 mitogen-activated protein kinase 8 Homo sapiens 214-217 23624748-8 2013 RU486 increased the phosphorylation of p38 MAPK and JNK, but p38 MAPK only was associated with RU486-mediated apoptosis. Mifepristone 0-5 mitogen-activated protein kinase 8 Homo sapiens 52-55 12837923-7 2003 JAK1 and JNK1 were two of the genes shown by the arrays to be down-regulated in RU486-treated endometrial explants. Mifepristone 80-85 mitogen-activated protein kinase 8 Homo sapiens 9-13 12837923-10 2003 These results show that components of two important signalling pathways in endometrium-the JAK/STAT pathway, and the JNK pathway-are altered by RU486. Mifepristone 144-149 mitogen-activated protein kinase 8 Homo sapiens 117-120