PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
34252545-3	2021	We demonstrated that diosgenin suppressed COX-2 in human non-small-cell lung carcinoma A549 cells via nuclear factor-kappa B (NF-kappaB) translocation and the effects were reversed by a glucocorticoid receptor antagonist, RU486.	Mifepristone	222-227	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	42-47	
25319133-8	2014	Of note, the inhibitory effects of PDN on the IL-1beta-induced expression of COX-2 and the activation of ERK-1/2 and JNK-1 in the HEI-OC1 cells were significantly diminished by RU486, a glucocorticoid receptor (GR) antagonist, suggesting that PDN exerts its inhibitory effects through GR.	Mifepristone	177-182	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	77-82	
24172143-6	2014	KEY RESULTS: The hypoxia-induced increase in COX-2 protein and mRNA levels and promoter activity were suppressed by dexamethasone, and this effect of dexamethasone was antagonized by the GR antagonist RU486.	Mifepristone	201-206	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	45-50	
21376132-3	2011	Human CG induction of immunoreactive COX-2 in the granulosa layer of mature Graafian follicles at hCG8h was reduced by RU486 treatment at hCG0h and trilostane treatment at hCG4h.	Mifepristone	119-124	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	37-42	
10508225-11	1999	After treatment with mifepristone, expression of COX-1 in glandular epithelium and COX-2 in luminal epithelium significantly decreased whilst the immunostaining for COX-2 in the perivascular cells remained strong.	Mifepristone	21-33	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	83-88	
10508225-11	1999	After treatment with mifepristone, expression of COX-1 in glandular epithelium and COX-2 in luminal epithelium significantly decreased whilst the immunostaining for COX-2 in the perivascular cells remained strong.	Mifepristone	21-33	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	165-170	
10508225-12	1999	This study shows the expression of both COX-1 and COX-2 during the implantation period and also indicates that treatment with mifepristone in early luteal phase impairs glandular epithelial function and endometrial receptivity.	Mifepristone	126-138	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	50-55	
9822711-7	1998	This dexamethasone-dependent repression involved a reduced COX-2 mRNA half-life, was blocked by actinomycin D or cycloheximide, and was antagonized by the steroid antagonist RU38486.	Mifepristone	174-181	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	59-64