PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
1332845-2	1992	Pretreatment of pituitary cell cultures with NaF (a guanyl nucleotide binding protein activator, 10 mM, 3 h) also decreased subsequent GnRH-stimulated LH release, and in addition, provoked a decrease in GnRH receptor number, an increase in GnRH receptor affinity, reduction of GnRH-stimulated IP production to basal levels, and an increase in the amount of LH released in response to stimulation with the calcium ionophore A23187.	Luteinizing Hormone	357-359	C-X-C motif chemokine ligand 8	Homo sapiens	45-48	
1332845-2	1992	Pretreatment of pituitary cell cultures with NaF (a guanyl nucleotide binding protein activator, 10 mM, 3 h) also decreased subsequent GnRH-stimulated LH release, and in addition, provoked a decrease in GnRH receptor number, an increase in GnRH receptor affinity, reduction of GnRH-stimulated IP production to basal levels, and an increase in the amount of LH released in response to stimulation with the calcium ionophore A23187.	Luteinizing Hormone	151-153	C-X-C motif chemokine ligand 8	Homo sapiens	45-48	
1332845-6	1992	GnRH-stimulated LH release was inhibited immediately after NaF pretreatment (1 microM GnRH-stimulated LH release in NaF-pretreated cells was 65% of control levels).	Luteinizing Hormone	16-18	C-X-C motif chemokine ligand 8	Homo sapiens	59-62	
1332845-6	1992	GnRH-stimulated LH release was inhibited immediately after NaF pretreatment (1 microM GnRH-stimulated LH release in NaF-pretreated cells was 65% of control levels).	Luteinizing Hormone	16-18	C-X-C motif chemokine ligand 8	Homo sapiens	116-119	
1332845-6	1992	GnRH-stimulated LH release was inhibited immediately after NaF pretreatment (1 microM GnRH-stimulated LH release in NaF-pretreated cells was 65% of control levels).	Luteinizing Hormone	102-104	C-X-C motif chemokine ligand 8	Homo sapiens	59-62	
1332845-6	1992	GnRH-stimulated LH release was inhibited immediately after NaF pretreatment (1 microM GnRH-stimulated LH release in NaF-pretreated cells was 65% of control levels).	Luteinizing Hormone	102-104	C-X-C motif chemokine ligand 8	Homo sapiens	116-119	
1332845-8	1992	A23187-provoked LH release was enhanced immediately after NaF pretreatment (30 microM A23187-stimulated LH release in NaF-pretreated cells was 170% of control levels).	Luteinizing Hormone	16-18	C-X-C motif chemokine ligand 8	Homo sapiens	118-121	
1332845-8	1992	A23187-provoked LH release was enhanced immediately after NaF pretreatment (30 microM A23187-stimulated LH release in NaF-pretreated cells was 170% of control levels).	Luteinizing Hormone	104-106	C-X-C motif chemokine ligand 8	Homo sapiens	58-61	
1332845-8	1992	A23187-provoked LH release was enhanced immediately after NaF pretreatment (30 microM A23187-stimulated LH release in NaF-pretreated cells was 170% of control levels).	Luteinizing Hormone	104-106	C-X-C motif chemokine ligand 8	Homo sapiens	118-121	
1315244-4	1992	We show that 3 h pretreatment of pituitary cell cultures with 10 mM NaF (a G protein activator), resulted in decreased gonadotrope responsiveness to subsequent GnRH treatment (3 h, 100 nM; 34.4 +/- 1.6% vs. 23.4 +/- 1.5% of total cellular LH).	Luteinizing Hormone	239-241	C-X-C motif chemokine ligand 8	Homo sapiens	68-71	
1597151-5	1992	Sodium fluoride (NaF)-stimulated IP accumulation was also inhibited by U-73122 (from 1539 +/- 132 dpm to 414 +/- 21 dpm) while LH release increased from 22.9 +/- 1.4% total cellular LH to 28.0 +/- 2.2%.	Luteinizing Hormone	127-129	C-X-C motif chemokine ligand 8	Homo sapiens	17-20	
1597151-9	1992	These results demonstrate that GnRH- as well as NaF-stimulated LH release can be uncoupled from IP production calling to question the role of IP3 as a second messenger for GnRH-stimulated LH release.	Luteinizing Hormone	63-65	C-X-C motif chemokine ligand 8	Homo sapiens	48-51	
7115353-3	1982	In plasma membranes from control cells in the presence of heat-inactivated human erythrocyte membranes both guanosine 5"-[beta, gamma-imido]triphosphate (p[NH]ppG) plus lutropin and NaF caused a 45--50-fold increase in cyclic AMP production over 30 min compared with 12--13 fold p[NH[ppG and 2--3-fold with lutropin alone.	Luteinizing Hormone	307-315	C-X-C motif chemokine ligand 8	Homo sapiens	182-185