PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 22075233-2 2011 The lead structures (5-benzylidenerhodanine 4a and 5-benzylidene-2,4-thiazolidinedione 4b) were identified in an in-house screening and these inhibited CEase with some selectivity over another serine hydrolase, acetylcholinesterase (AChE) (4a, CEase IC(50)=1.76 muM vs AChE IC(50)=5.14 muM and 4b, CEase IC(50)=5.89 muM vs AChE IC(50) >100 muM). 5-benzylidene thiazolidine-2,4-dione 51-86 acetylcholinesterase (Cartwright blood group) Homo sapiens 211-231 22075233-2 2011 The lead structures (5-benzylidenerhodanine 4a and 5-benzylidene-2,4-thiazolidinedione 4b) were identified in an in-house screening and these inhibited CEase with some selectivity over another serine hydrolase, acetylcholinesterase (AChE) (4a, CEase IC(50)=1.76 muM vs AChE IC(50)=5.14 muM and 4b, CEase IC(50)=5.89 muM vs AChE IC(50) >100 muM). 5-benzylidene thiazolidine-2,4-dione 51-86 acetylcholinesterase (Cartwright blood group) Homo sapiens 233-237