PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 8127678-4 1994 The expression of FAS3-lacZ reporter genes and the measurement of mRNA levels in regulatory mutants of phospholipid biosynthesis clearly indicated that FAS3 is regulated by inositol and choline. Inositol 173-181 acetyl-CoA carboxylase ACC1 Saccharomyces cerevisiae S288C 152-156 11486011-7 2001 Moreover, a reduction in Acc1 activity, caused by addition of soraphen A, provision of exogenous fatty acid, or conditional expression of ACC1, suppresses the inositol auxotrophy of snf1Delta strains. Inositol 159-167 acetyl-CoA carboxylase ACC1 Saccharomyces cerevisiae S288C 25-29 11486011-7 2001 Moreover, a reduction in Acc1 activity, caused by addition of soraphen A, provision of exogenous fatty acid, or conditional expression of ACC1, suppresses the inositol auxotrophy of snf1Delta strains. Inositol 159-167 acetyl-CoA carboxylase ACC1 Saccharomyces cerevisiae S288C 138-142 11486011-8 2001 Together, these findings indicate that the inositol auxotrophy of snf1Delta strains arises in part from elevated Acc1 activity and that a reduction in this activity restores INO1 expression in these strains. Inositol 43-51 acetyl-CoA carboxylase ACC1 Saccharomyces cerevisiae S288C 113-117 8098706-7 1993 ACC1 transcription was repressed 3-fold by lipid precursors, inositol and choline, and was also controlled by regulatory factors Ino2p, Ino4p, and Opi1p, providing evidence that the key step of fatty acid synthesis is regulated in conjunction with phospholipid synthesis at the level of gene expression. Inositol 61-69 acetyl-CoA carboxylase ACC1 Saccharomyces cerevisiae S288C 0-4 8098706-8 1993 The 5"-untranslated region of the ACC1 gene contains a sequence reminiscent of an inositol/choline-responsive element identified in genes encoding phospholipid biosynthetic enzymes. Inositol 82-90 acetyl-CoA carboxylase ACC1 Saccharomyces cerevisiae S288C 34-38