PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 1905717-2 1991 GTP cyclohydrolase I, an enzyme that catalyzes the first reaction in the pathway for the biosynthesis of pterin compounds, was purified from of C3H mouse liver by 192-fold to apparent homogeneity, using Ultrogel AcA34, DEAE-Trisacryl, and GTP-agarose gels. Pterins 105-111 GTP cyclohydrolase 1 Mus musculus 0-20 2775176-12 1989 These studies demonstrate that micromolar levels of reduced pterins may have regulatory effects on GTP cyclohydrolase I and that a mouse mutant is available that has low enough activity to be considered as a model for human atypical phenylketonuria. Pterins 60-67 GTP cyclohydrolase 1 Mus musculus 99-119