PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 3349105-0 1988 Inhibition of GTP cyclohydrolase I by pterins. Pterins 38-45 GTP cyclohydrolase 1 Homo sapiens 14-34 23100563-2 2013 We demonstrate that Escherichia coli K1 infection of human brain microvascular endothelial cells (HBMECs) induces the expression of guanosine triphosphate cyclohydrolase (GCH1), the rate-limiting enzyme in pterin synthesis, thereby elevating levels of biopterin. Pterins 206-212 GTP cyclohydrolase 1 Homo sapiens 171-175 3106526-0 1986 Interferon-gamma enhances biosynthesis of pterins in peripheral blood mononuclear cells by induction of GTP-cyclohydrolase I activity. Pterins 42-49 GTP cyclohydrolase 1 Homo sapiens 104-124 7545102-7 1995 NO synthesis was prevented by an inhibitor of GTPCH, 2,4-diamino-6-hydroxypyrimidine, and this inhibition was completely reversed by administration of sepiapterin, a substrate for BH4 synthesis via pterin salvage pathway. Pterins 156-162 GTP cyclohydrolase 1 Homo sapiens 46-51