PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
12804014-1	2003	Human macrophages release the pterin, 7,8-dihydroneopterin when exposed to the immune stimulant gamma-interferon (IFN-gamma).	Pterins	30-36	interferon gamma	Homo sapiens	114-123	
12804014-5	2003	The extracellular pterin concentration increased from 0 to 16 nM with IFN-gamma stimulation, while the intracellular concentration increased from 0.21 to 1.69 nmol/mg cell protein.	Pterins	18-24	interferon gamma	Homo sapiens	70-79	
3106526-2	1986	Our study aimed at investigating the biosynthesis of unconjugated pterins in highly purified human macrophages and T lymphocytes before and during stimulation with supernatants of activated T cells or with recombinant human interferon-gamma (IFN-gamma) by monitoring the following parameters: substrate concentration (GTP, guanosine triphosphate), activity of the enzyme initiating the biosynthesis of pterins (GTP-cyclohydrolase I) and product concentrations of total neopterin, biopterin, and pterin.	Pterins	66-72	interferon gamma	Homo sapiens	224-240	
3106526-10	1986	Thus, it appears that IFN-gamma selectively stimulates the early steps of pterin biosynthesis in macrophages, thereby leading to accumulation and excretion of dihydroneopterin and neopterin.	Pterins	74-80	interferon gamma	Homo sapiens	22-31	
3087039-1	1986	We have recently shown that interferon-gamma is capable of activating the key enzyme of pterin biosynthesis in macrophages.	Pterins	88-94	interferon gamma	Homo sapiens	28-44	
3106526-0	1986	Interferon-gamma enhances biosynthesis of pterins in peripheral blood mononuclear cells by induction of GTP-cyclohydrolase I activity.	Pterins	42-49	interferon gamma	Homo sapiens	0-16	
3106526-2	1986	Our study aimed at investigating the biosynthesis of unconjugated pterins in highly purified human macrophages and T lymphocytes before and during stimulation with supernatants of activated T cells or with recombinant human interferon-gamma (IFN-gamma) by monitoring the following parameters: substrate concentration (GTP, guanosine triphosphate), activity of the enzyme initiating the biosynthesis of pterins (GTP-cyclohydrolase I) and product concentrations of total neopterin, biopterin, and pterin.	Pterins	66-73	interferon gamma	Homo sapiens	224-240