PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 16532389-6 2006 Here, we report that mice deficient in the Spr gene (Spr(-/-)) display disturbed pterin profiles and greatly diminished levels of dopamine, norepinephrine, and serotonin, indicating that SPR is essential for homeostasis of BH(4) and for the normal functions of BH(4)-dependent enzymes. Pterins 81-87 sepiapterin reductase Mus musculus 43-46 16532389-6 2006 Here, we report that mice deficient in the Spr gene (Spr(-/-)) display disturbed pterin profiles and greatly diminished levels of dopamine, norepinephrine, and serotonin, indicating that SPR is essential for homeostasis of BH(4) and for the normal functions of BH(4)-dependent enzymes. Pterins 81-87 sepiapterin reductase Mus musculus 53-56 9405351-0 1997 The 1.25 A crystal structure of sepiapterin reductase reveals its binding mode to pterins and brain neurotransmitters. Pterins 82-89 sepiapterin reductase Mus musculus 32-53 1967605-6 1990 (c) NS7 antibody was shown to bind to a wide range of pterin-requiring enzymes: phenylalanine, tyrosine and tryptophan hydroxylases, dihydropteridine reductase, dihydrofolate reductase, and sepiapterin reductase. Pterins 54-60 sepiapterin reductase Mus musculus 190-211